Sugi Predict

Sugi Predict / Compounds / SCHEMBL2148722

SCHEMBL2148722

SCHEMBL2148722

CCCS(=O)(=O)c1ccc(N)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.69
▸ CA2 P00918 7/20 0.58
▸ CA12 O43570 6/20 0.58
▸ CA1 P00915 6/20 0.58
▸ CA9 Q16790 6/20 0.58
▸ TSHR P16473 4/20 0.50
▸ CYP3A4 P08684 3/20 0.50
▸ CYP2C9 P11712 2/20 0.50
▸ LMNA P02545 1/20 0.50
▸ MPO P05164 1/20 0.50
▸ HTR6 P50406 1/20 0.50
▸ TDP1 Q9NUW8 2/20 0.48
▸ CA14 Q9ULX7 2/20 0.48
▸ USP2 O75604 1/20 0.48
▸ CA4 P22748 1/20 0.48
▸ CA6 P23280 1/20 0.48
▸ CA5A P35218 1/20 0.48
▸ CA7 P43166 1/20 0.48
▸ CA13 Q8N1Q1 1/20 0.48
▸ AGO2 Q9UKV8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7282032 0.88 GAA (0.64) GAACA2CA12CA1CA9
SCHEMBL8878487 0.84 GAA (0.60) GAACA2CA12CA1CA9
SCHEMBL22471791 0.84 GAA (0.60) GAACA2CA12CA1CA9
SCHEMBL2123298 0.84 GAA (0.60) GAACA2CA12CA1CA9
SCHEMBL11131722 0.84 GAA (0.60) GAACA2CA12CA1CA9
SCHEMBL8158540 0.84 GAA (0.60) GAACA2CA12CA1CA9
SCHEMBL11213098 0.84 GAA (0.60) GAACA2CA12CA1CA9
SCHEMBL1973873 0.84 GAA (0.95) GAACA2CA12CA1CA9
SCHEMBL29980399 0.82 GAA (0.61) GAACA2CA12CA1CA9
SCHEMBL10702964 0.80 GAA (0.59) GAACA2CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661289-B1 Vinyl carboxamide derivatives as insecticides and acaricides SYNGENTA PARTICIPATIONS AG (CH) 2004-03-03 — — EP claimed
CN-103666487-B Crystal aligning agent, liquid crystal orienting film and liquid crystal display cells JSR株式会社 2016-08-24 — — CN disclosed
EP-2342185-B1 SULFON SUBSTITUTED ANILINE PYRIMIDINE DERIVATIVES AS CDK INHIBITORS, THEIR MANUFACTURE AND USE AS MEDICINE BAYER IP GMBH (DE) 2016-01-13 — — EP disclosed
US-8802686-B2 Sulfone-substituted anilinopyrimidine derivatives as CDK inhibitors, the production thereof, and use as a medicine BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-08-12 — — US disclosed
US-20110251222-A1 SULFONE-SUBSTITUTED ANILINOPYRIMIDINE DERIVATIVES AS CDK INHIBITORS, THE PRODUCTION THEREOF, AND USE AS A MEDICINE BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2011-10-13 — — US disclosed
EP-2342185-A1 SULFONE-SUBSTITUTED ANILINOPYRIMIDINE DERIVATIVES AS CDK INHIBITORS, THE PRODUCTION THEREOF, AND USE AS A MEDICINE Bayer Schering Pharma Aktiengesellschaft (DE) 2011-07-13 — — EP disclosed
US-20100317653-A1 OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS ASTRAZENECA AB (SE) 2010-12-16 — — US disclosed
US-7795283-B2 Oxadiazole derivative as DGAT inhibitors ASTRAZENECA AB (SE) 2010-09-14 — — US disclosed
WO-2010046034-A1 SULFONE-SUBSTITUTED ANILINOPYRIMIDINE DERIVATIVES AS CDK INHIBITORS, THE PRODUCTION THEREOF, AND USE AS A MEDICINE BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2010-04-29 — — WO disclosed
EP-2179992-A1 Sulfon substituted aniline pyrimidine derivatives as CDK inhibitors, their manufacture and use as medicine Bayer Schering Pharma Aktiengesellschaft (DE) 2010-04-28 — — EP disclosed
US-5545630-A PESTICIDES CIBA-GEIGY CORPORATION (US) 1996-08-13 — — US disclosed
EP-0661289-A1 Vinyl carboxamide derivatives as insecticides and acaricides CIBA-GEIGY AG (CH) 1995-07-05 — — EP disclosed
US-4900656-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1990-02-13 — — US disclosed
US-4741994-A PHENOL OR SULFONAMIDE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1988-05-03 — — US disclosed
EP-0126455-B1 SILVER HALIDE PHOTOGRAPHIC EMULSION FUJI PHOTO FILM CO., LTD. (JP) 1988-01-20 — — EP disclosed
US-4513081-A SENSITIZING METHINE DYE AND CYAN COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1985-04-23 — — US disclosed
EP-0126455-A2 Silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 1984-11-28 — — EP disclosed
EP-0038439-B1 DYESTUFF MIXTURES, METHOD FOR THEIR PREPARATION, THE COMPONENT DYESTUFFS AND THEIR USE IN DYEING AND PRINTING SYNTHETIC, HYDROPHOBIC FIBRE MATERIAL CASSELLA Aktiengesellschaft (DE) 1983-05-04 — — EP disclosed
EP-0038439-A1 Dyestuff mixtures, method for their preparation, the component dyestuffs and their use in dyeing and printing synthetic, hydrophobic fibre material CASSELLA Aktiengesellschaft (DE) 1981-10-28 — — EP disclosed
US-4207233-A Azo dyes containing a thiazole component BASF AKTIENGESELLSCHAFT (DE) 1980-06-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317653-A1 OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS DGAT1, DGAT2, GPR119 GAA 171/4885CA2 4679/4885CA12 4830/4885
US-20110251222-A1 SULFONE-SUBSTITUTED ANILINOPYRIMIDINE DERIVATIVES AS CDK INHIBITORS, THE PRODUCTION THEREOF, AND USE AS A MEDICINE CDK6, CDK4, CDK2 GAA 2013/4885CA2 3420/4885CA12 4361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.