Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 7/20 | 0.40 |
| ▸ | MC4R | P32245 | 6/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2148833 | 0.91 | MC1R (0.47) | MC1RMC4RCTSKALDH1A1TSHR | |
| SCHEMBL2148882 | 0.83 | MC1R (0.40) | MC1RMC4RALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2149100 | 0.81 | MC1R (0.50) | MC1RMC4RMAPT | |
| SCHEMBL2149007 | 0.79 | MC1R (0.37) | MC1RMC4RALDH1A1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL1310165 | 0.75 | MC1R (0.49) | MC1RMC4R | |
| SCHEMBL1312669 | 0.74 | GPR119 (0.39) | MC1RMC4RMAPTSMN1; SMN2 | |
| SCHEMBL2148982 | 0.74 | MC1R (0.57) | MC1RMC4RKMT2AALDH1A1LMNA | |
| SCHEMBL2148899 | 0.74 | NPC1 (0.34) | CTSKKMT2AALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL1310666 | 0.73 | MC1R (0.47) | MC1RMC4RCTSKKMT2AMAPT | |
| SCHEMBL16445371 | 0.72 | MC1R (0.62) | MC1RMC4RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342194-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010052253-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-05-14 | — | — | WO | disclosed |