Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 10/20 | 0.46 |
| ▸ | CA2 | P00918 | 10/20 | 0.46 |
| ▸ | CA9 | Q16790 | 9/20 | 0.46 |
| ▸ | CA12 | O43570 | 8/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11128883 | 0.81 | GAA (0.57) | GAATSHRCYP3A4LMNAMPO | |
| SCHEMBL10524502 | 0.79 | CA2 (0.52) | GAALMNACA1CA2CA9 | |
| SCHEMBL3626870 | 0.79 | CTSK (0.59) | GAACYP3A4CYP2C9CA1CA2 | |
| SCHEMBL10592713 | 0.79 | TDP1 (0.55) | GAATSHRCYP3A4LMNACYP2C9 | |
| SCHEMBL4012964 | 0.79 | KMT2A (0.44) | CA1CA2ALDH1A1PNMTMMP2 | |
| SCHEMBL9820029 | 0.79 | NPC1 (0.48) | CYP3A4CA1CA2CA9CA12 | |
| SCHEMBL2548723 | 0.79 | CTSK (0.59) | GAACYP3A4CYP2C9CA1CA2 | |
| SCHEMBL13183908 | 0.79 | PLCG1 (0.59) | TSHRCYP3A4LMNACYP2C9CA1 | |
| SCHEMBL9002759 | 0.79 | CA1 (0.52) | GAALMNACA1CA2CA9 | |
| SCHEMBL10181443 | 0.79 | ALDH1A1 (0.42) | GAALMNACA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342185-B1 | SULFON SUBSTITUTED ANILINE PYRIMIDINE DERIVATIVES AS CDK INHIBITORS, THEIR MANUFACTURE AND USE AS MEDICINE | BAYER IP GMBH (DE) | 2016-01-13 | — | — | EP | disclosed |
| US-8802686-B2 | Sulfone-substituted anilinopyrimidine derivatives as CDK inhibitors, the production thereof, and use as a medicine | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-08-12 | — | — | US | disclosed |
| US-20110251222-A1 | SULFONE-SUBSTITUTED ANILINOPYRIMIDINE DERIVATIVES AS CDK INHIBITORS, THE PRODUCTION THEREOF, AND USE AS A MEDICINE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-10-13 | — | — | US | disclosed |
| EP-2342185-A1 | SULFONE-SUBSTITUTED ANILINOPYRIMIDINE DERIVATIVES AS CDK INHIBITORS, THE PRODUCTION THEREOF, AND USE AS A MEDICINE | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010046034-A1 | SULFONE-SUBSTITUTED ANILINOPYRIMIDINE DERIVATIVES AS CDK INHIBITORS, THE PRODUCTION THEREOF, AND USE AS A MEDICINE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-29 | — | — | WO | disclosed |
| EP-2179992-A1 | Sulfon substituted aniline pyrimidine derivatives as CDK inhibitors, their manufacture and use as medicine | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-04-28 | — | — | EP | disclosed |
| EP-0134192-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1987-09-30 | — | — | EP | disclosed |
| US-4677199-A | Reactive dyes containing substituted 4-fluoropyridaz-6-one radicals | BASF AKTIENGESELLSCHAFT (DE) | 1987-06-30 | — | — | US | disclosed |
| EP-0119441-B1 | REACTIVE DYES WITH SUBSTITUTED 4-FLUOROPYRIDAZ-6-ONE GROUPS | BASF Aktiengesellschaft (DE) | 1987-02-25 | — | — | EP | disclosed |
| US-4563520-A | COLORFAST BROWN SYEINGS ON LEATHER | BASF AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |
| EP-0134192-A1 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-03-13 | — | — | EP | disclosed |
| US-4491543-A | BROWN DYES ON LEATHER | BASF AKTIENGESELLSCHAFT (DE) | 1985-01-01 | — | — | US | disclosed |
| EP-0068245-B1 | DYESTUFFS CONTAINING SULPHONIC ACID GROUPS | BASF Aktiengesellschaft (DE) | 1984-10-31 | — | — | EP | disclosed |
| EP-0119441-A2 | Reactive dyes with substituted 4-fluoropyridaz-6-one groups | BASF Aktiengesellschaft (DE) | 1984-09-26 | — | — | EP | disclosed |
| EP-0031099-B1 | COMPOUNDS WITH REACTIVE RESTS AND THEIR USE IN DYEING FIBRES | BASF Aktiengesellschaft (DE) | 1984-07-18 | — | — | EP | disclosed |
| EP-0083052-A1 | Reactive disazo dyes, process for their preparation and their use in dyeing and printing hydroxyl or nitrogen containing fibrous materials | BAYER AG (DE) | 1983-07-06 | — | — | EP | disclosed |
| EP-0078007-A1 | Metallised polyazo dyestuffs | BASF Aktiengesellschaft (DE) | 1983-05-04 | — | — | EP | disclosed |
| EP-0068245-A1 | Dyestuffs containing sulphonic acid groups | BASF Aktiengesellschaft (DE) | 1983-01-05 | — | — | EP | disclosed |
| EP-0066714-A2 | Reactive dyestuffs | BASF Aktiengesellschaft (DE) | 1982-12-15 | — | — | EP | disclosed |
| EP-0031099-A2 | Compounds with reactive rests and their use in dyeing fibres | BASF Aktiengesellschaft (DE) | 1981-07-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251222-A1 | SULFONE-SUBSTITUTED ANILINOPYRIMIDINE DERIVATIVES AS CDK INHIBITORS, THE PRODUCTION THEREOF, AND USE AS A MEDICINE | CDK6, CDK4, CDK2 | GAA 2013/4885TSHR 3730/4885CYP3A4 452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.