Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4277339 | 0.88 | F2 (0.34) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3466455 | 0.73 | ALDH1A1 (0.38) | F2PRSS1PRSS2PRSS3TP53 | |
| SCHEMBL1864288 | 0.73 | APP (0.46) | TP53CYP2C19 | |
| SCHEMBL8314518 | 0.73 | ATR (0.35) | — | |
| SCHEMBL6014 | 0.73 | TP53 (0.35) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL23804917 | 0.73 | F2 (0.33) | F2PRSS1PRSS2PRSS3CYP2C19 | |
| SCHEMBL9883956 | 0.71 | LMNA (0.42) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL5498553 | 0.71 | ALDH1A1 (0.36) | F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8710297 | 0.71 | TP53 (0.34) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL4313342 | 0.71 | APP (0.44) | TP53CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787442-B2 | Modulators of indoleamine 2,3-dioxygenase | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-09-29 | — | — | US | disclosed |
| US-20190322652-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787442-B2 | Modulators of indoleamine 2,3-dioxygenase | IDO1, IDO2, TPH1 | F2 3638/4885PRSS1 1362/4885PRSS2 2041/4885 |
| US-20190322652-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | IDO1, IDO2, TPH1 | F2 3638/4885PRSS1 1362/4885PRSS2 2041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.