Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 7/20 | 0.50 |
| ▸ | MC4R | P32245 | 7/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2148833 | 0.88 | MC1R (0.47) | MC1RMC4RAPPGAAGRIN2B | |
| SCHEMBL2148981 | 0.81 | MC1R (0.40) | MC1RMC4RMAPT | |
| SCHEMBL2149032 | 0.79 | MC1R (0.62) | MC1RMC4RAPPGAAMAPT | |
| SCHEMBL2149007 | 0.76 | MC1R (0.37) | MC1RMC4RAPPGAAGRIN2B | |
| Trifluoroacetic Acid SCHEMBL1311384 | 0.75 | MC1R (0.58) | MC1RMC4RPOLB | |
| SCHEMBL1311665 | 0.75 | MC1R (0.58) | MC1RMC4RAPPGAAMAPT | |
| SCHEMBL16445351 | 0.75 | MC1R (0.73) | MC1RMC4RAPPGAAMAPT | |
| SCHEMBL2149249 | 0.71 | MC1R (0.49) | MC1RMC4RAPPGRIN2B | |
| SCHEMBL3731642 | 0.69 | MC1R (0.47) | MC1RMC4RAPPGRIN2B | |
| SCHEMBL1311007 | 0.68 | MC4R (0.42) | MC1RMC4RAPPCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342194-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-07-13 | — | — | EP | disclosed |