SCHEMBL21490330

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29442988	1.00	PTPN1 (0.47)	PTPN1KYAT1KYAT3AADATALDH1A1
	SCHEMBL4999428	0.89	KYAT1 (0.45)	KYAT1KYAT3AADATALDH1A1STS
	SCHEMBL29442994	0.89	KYAT1 (0.45)	KYAT1KYAT3AADATALDH1A1STS
	SCHEMBL21447269	0.86	PTPN1 (0.48)	PTPN1HDAC8PDE4BMMP3MMP8
	SCHEMBL19902536	0.86	PTPN1 (0.48)	PTPN1AADATHDAC8PDE4BLMNA
	SCHEMBL29442998	0.83	DRD2 (0.51)	PTPN1LMNA
	SCHEMBL2827018	0.83	DRD2 (0.51)	PTPN1LMNA
	SCHEMBL2827020	0.83	DRD2 (0.51)	PTPN1LMNA
	SCHEMBL13170457	0.82	PTPN1 (0.45)	PTPN1HDAC8PDE4BNR1H2NR1H3
	SCHEMBL21470656	0.82	PTPN1 (0.41)	PTPN1ALDH1A1STSHDAC8PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.