Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5502790 | 0.83 | SMN1; SMN2 (0.47) | FAAHTSHRSMN1; SMN2CYP2C19NPC1 | |
| SCHEMBL2320404 | 0.82 | FAAH (0.59) | FAAHSMN1; SMN2MAPK1CTSANPC1 | |
| SCHEMBL1721258 | 0.82 | SMN1; SMN2 (0.39) | FAAHTSHRSMN1; SMN2MAPK1CYSLTR2 | |
| SCHEMBL5088792 | 0.80 | CTSA (0.51) | POLBSMN1; SMN2MAPK1CYP1A2CYP2C19 | |
| SCHEMBL5199852 | 0.80 | L3MBTL1 (0.40) | FAAHTSHRPOLBSMN1; SMN2CTSA | |
| SCHEMBL6251048 | 0.78 | FAAH (0.41) | FAAHTSHRSMN1; SMN2MAPK1CTSA | |
| SCHEMBL6015437 | 0.76 | ESR1 (0.41) | FAAHTSHRSMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL5089567 | 0.76 | CTSA (0.54) | CTSA | |
| SCHEMBL5499794 | 0.76 | POLB (0.57) | FAAHPOLBSMN1; SMN2MAPK1NPC1 | |
| SCHEMBL14040614 | 0.75 | SMN1; SMN2 (0.57) | FAAHTSHRPOLBSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342194-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010052253-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-05-14 | — | — | WO | disclosed |