SCHEMBL2149073

SCHEMBL2149073

C=CCc1c2ccccc2c(CC=C)c2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
PDE4B Q07343 2/20 0.38
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
ALDH1A1 P00352 4/20 0.37
GAA P10253 2/20 0.37
IMPDH2 P12268 1/20 0.36
CASP3 P42574 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.33
TSHR P16473 2/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
HPGD P15428 1/20 0.33
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
XDH P47989 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29853701 1.00 KDM4E (0.38) KDM4EMEN1KMT2APDE4BGABRA1
SCHEMBL2361528 0.92 KDM4E (0.37) KDM4EMEN1KMT2APDE4BGABRA1
SCHEMBL3800938 0.90 KDM4E (0.36) KDM4EMEN1KMT2APDE4BGABRA1
SCHEMBL23527397 0.89 CYP3A4 (0.46) KDM4EMEN1KMT2APDE4BALDH1A1
SCHEMBL11666112 0.89 PDE4B (0.37) KDM4EMEN1KMT2APDE4BGABRA1
SCHEMBL11663091 0.85 PADI4 (0.44) KDM4EMEN1KMT2APDE4BGAA
SCHEMBL2143244 0.84 HTR2A (0.54) KDM4EMEN1KMT2AALDH1A1IMPDH2
SCHEMBL30300202 0.84 HTR2A (0.54) KDM4EMEN1KMT2AALDH1A1IMPDH2
SCHEMBL9273537 0.82 KDM4E (0.52) KDM4EMEN1KMT2AALDH1A1GAA
SCHEMBL3806608 0.80 IMPDH2 (0.36) KDM4EMEN1KMT2AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4091578-B1 METHOD FOR PRODUCING PLATE DENTURE TOKUYAMA DENTAL CORP (JP) 2024-10-09 EP disclosed
US-11857385-B2 Method of producing plate denture, curable composition for stereolithography, and plate denture production kit TOKUYAMA DENTAL CORPORATION (JP) 2024-01-02 US disclosed
CN-114929158-B Method for producing denture, curable composition for photoforming, and kit for producing denture 株式会社德山齿科 2023-10-20 CN disclosed
US-20230137898-A1 METHOD OF PRODUCING PLATE DENTURE, CURABLE COMPOSITION FOR STEREOLITHOGRAPHY, AND PLATE DENTURE PRODUCTION KIT TOKUYAMA DENTAL CORPORATION (JP) 2023-05-04 US disclosed
EP-4091578-A1 METHOD FOR PRODUCING PLATE DENTURE, CURABLE STEREOLITHOGRAPHIC COMPOSITION, AND PLATE DENTURE PRODUCTION KIT Tokuyama Dental Corporation (JP) 2022-11-23 EP disclosed
CN-114929158-A Method for producing a denture, curable composition for photo-molding, and kit for producing a denture 株式会社德山齿科 2022-08-19 CN disclosed
US-20220127385-A1 COMPOUND HAVING POLYCYCLIC AROMATIC SKELETON, AND ENDOPEROXIDE COMPOUND OF SAME KAWASAKI KASEI CHEMICALS LTD. (JP) 2022-04-28 US disclosed
CN-113454090-A Compound having polycyclic aromatic skeleton and endoperoxide compound thereof 川崎化成工业株式会社 2021-09-28 CN disclosed
CN-103988313-A Method for manufacturing silicon substrate having textured structure TOKUYAMA CORPROATION 2014-08-13 CN disclosed
US-20120296085-A1 CHEMILUMINESCENT DYES AND DYE-STAINED PARTICLES UNIVERSITY OF NOTRE DAME DU LAC (US) 2012-11-22 US disclosed
US-6361885-B1 ANODES AND CATHODES FOR ELECTROLUMINESCENT DEVICE ORGANIC DISPLAY TECHNOLOGY 2002-03-26 US disclosed
US-6344284-B1 ORGANO-SILOXANE (CARBOSILANE) POLYMER HAVING A MAIN CHAIN COMPRISING ANTHRACENE AND/OR PENTACENE OPTIONALLY DOPED WITH A PORPHYRIN, AN AROMATIC TERTIARY AMINE OR A DYE ORGANIC DISPLAY TECHNOLOGY 2002-02-05 US disclosed
US-6165383-A Useful precursors for organic electroluminescent materials and devices made from such materials ORGANIC DISPLAY TECHNOLOGY (US) 2000-12-26 US disclosed
WO-2000031208-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ORGANIC DISPLAY TECHNOLOGY (US) 2000-06-02 WO disclosed
US-4734824-A MONOOLEFIN OR DIOLEFIN HAVING THREE CONDENSED OR NONCONDENSED AROMATIC RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-03-29 US disclosed
EP-0154993-B1 ELECTRICAL INSULATING OIL AND ELECTRICAL APPLIANCES IMPREGNATED WITH THE SAME NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-03-09 EP disclosed
US-4621302-A MONO-OR DIOLEFIN HAVING THREE CONDENSED OR NON-CONDENSED AROMATIC RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-11-04 US disclosed
EP-0154993-A1 Electrical insulating oil and electrical appliances impregnated with the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-09-18 EP disclosed
US-4094968-A ANTIANAPHYLACTICS, ASTHMA, RHINITIS BURROUGHS WELLCOME CO. (US) 1978-06-13 US disclosed
US-3939276-A ANTHRAQUINONES, ASTHMA, ANTIALLERGENS BURROUGHS WELLCOME CO. (US) 1976-02-17 US disclosed