SCHEMBL2143244

SCHEMBL2143244

C=CCc1c2ccccc2cc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
ALDH1A1 P00352 5/20 0.39
HSD17B10 Q99714 4/20 0.39
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
IMPDH2 P12268 1/20 0.39
CYP1A2 P05177 3/20 0.38
HPGD P15428 3/20 0.38
KDM4E B2RXH2 3/20 0.38
CYP2C19 P33261 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
GLA P06280 1/20 0.38
GPR35 Q9HC97 2/20 0.37
POLB P06746 2/20 0.37
CYP3A4 P08684 1/20 0.36
ERBB2 P04626 1/20 0.36
FYN P06241 1/20 0.36
MAOA P21397 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30300202 1.00 HTR2A (0.54) HTR2AL3MBTL1ALDH1A1HSD17B10HIF1A
SCHEMBL3806608 0.84 IMPDH2 (0.36) HTR2AL3MBTL1ALDH1A1HSD17B10HIF1A
SCHEMBL5138488 0.84 HTR2A (0.42) HTR2AL3MBTL1ALDH1A1HSD17B10HIF1A
SCHEMBL2149073 0.84 KDM4E (0.38) L3MBTL1ALDH1A1IMPDH2HPGDKDM4E
SCHEMBL29853701 0.84 KDM4E (0.38) L3MBTL1ALDH1A1IMPDH2HPGDKDM4E
SCHEMBL23527418 0.82 NR1I2 (0.40) HTR2AL3MBTL1ALDH1A1HSD17B10CYP1A2
SCHEMBL11008319 0.81 TRPM4 (0.46) HTR2AL3MBTL1ALDH1A1HSD17B10CYP1A2
SCHEMBL7195959 0.81 CYP1A2 (0.40) HTR2AL3MBTL1ALDH1A1HSD17B10IMPDH2
SCHEMBL2184374 0.80 HTR2A (0.43) HTR2AL3MBTL1ALDH1A1HSD17B10HIF1A
SCHEMBL30114966 0.80 KMT2A (0.41) HTR2AL3MBTL1ALDH1A1HSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
US-12379611-B2 Diffractive contact lenses ALCON INC. (CH) 2025-08-05 US claimed
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP claimed
US-20230004023-A1 DIFFRACTIVE CONTACT LENSES ALCON INC. (CH) 2023-01-05 US claimed
WO-2022263994-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2022-12-22 WO claimed
US-6780953-B2 ACRYLIC POLYMER PARTICULARLY USEFUL IN A SUBMICROLITHOGRAPHIC PROCESS USING KRF (248 NM) OR ARF (193 NM) LASERS AS LIGHT SOURCE HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2004-08-24 US claimed
US-6602650-B2 9-anthracenemethylimineethylacrylate and hydroxy (meth)acrylate polymer HYNIX SEMICONDUCTOR INC (KR) 2003-08-05 US claimed
US-6599678-B2 For producing semiconductor device HYNIX SEMICONDUCTOR INC (KR) 2003-07-29 US claimed
US-20030118736-A1 Organic polymer for anti-reflective coating layer and preparation thereof HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2003-06-26 US claimed
US-6582883-B2 Acrylic ester with anthracene oxime side group copolymerized HYNIX SEMICONDUCTOR INC. (KR) 2003-06-24 US claimed
US-6489432-B2 POLYACETAL FORMED BY THE ACETALIZATION OF A POLYACRYLEIN WITH AN ALCOHOL; REACTION WITH A CROSSLINKING AGENT, ESPECIALLY AN ANTHRACENYLMETHYL ACRYLATE-HYDROXYALKYL ACRYLATE COPOLYMER; SEMICONDUCTOR COATINGS HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-12-03 US claimed
US-20020132183-A1 Organic anti-reflective coating material and its preparation HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-09-19 US claimed
US-20020127789-A1 Organic anti-reflective coating polymer, anti-reflective coating composition comprising the same and method of preparation thereof HYNIX SEMICONDUCTOR INC. (KR) 2002-09-12 US claimed
US-20020123586-A1 Organic anti-reflective coating polymer, anti-reflective coating composition methods of preparation thereof HYNIX SEMICONDUCTOR INC. (KR) 2002-09-05 US claimed
US-20020093069-A1 Organic anti-reflective coating polymer, anti-reflective coating composition and methods of preparation thereof HYNIX SEMICONDUCTOR INC. (KR) 2002-07-18 US claimed
US-20020090452-A1 Organic anti-reflective coating polymer, anti-reflective coating composition and methods of preparation thereof HYNIX SEMICONDUCTOR INC. (KR) 2002-07-11 US claimed
US-6368768-B1 ACRYLATE ESTER COPOLYMER HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-04-09 US claimed
US-20010049429-A1 Organic anti-reflective coating polymer and preparation thereof HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2001-12-06 US claimed
US-20010043992-A1 Organic polymer for anti-reflective coating layer and preparation thereof HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2001-11-22 US claimed
US-20010034427-A1 Organic anti-reflective coating polymer and preparation thereof HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2001-10-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES LBR, CRYZ, CRYAA HTR2A 4455/4885L3MBTL1 3896/4885ALDH1A1 1323/4885
US-20030118736-A1 Organic polymer for anti-reflective coating layer and preparation thereof CAD, PARG, LAS1L HTR2A 3131/4885L3MBTL1 1678/4885ALDH1A1 2906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.