SCHEMBL2361528

SCHEMBL2361528

C=CCc1c(CC=C)c(CC=C)c2ccccc2c1CC=C

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
PDE4B Q07343 2/20 0.37
ALDH1A1 P00352 2/20 0.36
GAA P10253 2/20 0.36
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
IMPDH2 P12268 1/20 0.35
CASP3 P42574 1/20 0.33
MAPT P10636 2/20 0.33
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
RAB9A P51151 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29853701 0.92 KDM4E (0.38) KDM4EMEN1KMT2APDE4BALDH1A1
SCHEMBL2149073 0.92 KDM4E (0.38) KDM4EMEN1KMT2APDE4BALDH1A1
SCHEMBL3800938 0.87 KDM4E (0.36) KDM4EMEN1KMT2APDE4BALDH1A1
SCHEMBL28972920 0.83 GABRA1 (0.41) KDM4EMEN1KMT2APDE4BALDH1A1
SCHEMBL23527397 0.81 CYP3A4 (0.46) KDM4EMEN1KMT2APDE4BALDH1A1
SCHEMBL11666112 0.81 PDE4B (0.37) KDM4EMEN1KMT2APDE4BALDH1A1
SCHEMBL5919653 0.78 GABRA1 (0.45) KDM4EMEN1KMT2AALDH1A1GAA
SCHEMBL11230515 0.78 GABRA1 (0.38) KDM4EMEN1KMT2APDE4BGAA
SCHEMBL11663091 0.78 PADI4 (0.44) KDM4EMEN1KMT2APDE4BGAA
SCHEMBL7189859 0.78 SMN1; SMN2 (0.40) KDM4EMEN1KMT2AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2744832-B2 1998-04-28 JP claimed
EP-0444056-B1 PROCESS FOR SELECTIVE MANUFACTURE OF 2,6-DIALKYLNAPHTHALENES CATALYTICA INC (US) 1994-06-08 EP claimed
EP-0444056-A4 PROCESS FOR SELECTIVE MANUFACTURE OF 2,6-DIALKYLNAPHTHALENES 1991-11-06 EP claimed
EP-0444056-A1 PROCESS FOR SELECTIVE MANUFACTURE OF 2,6-DIALKYLNAPHTHALENES. CATALYTICA INC (US) 1991-09-04 EP claimed
WO-1990003960-A1 PROCESS FOR SELECTIVE MANUFACTURE OF 2,6-DIALKYLNAPHTHALENES CATALYTICA, INC. (US) 1990-04-19 WO claimed
EP-1389609-B1 METHOD OF PURIFYING AROMATIC POLYCARBOXYLIC ACID MITSUBISHI GAS CHEMICAL CO (JP) 2013-09-11 EP disclosed
EP-2194037-B1 Process for producing a high purity aromatic polycarboxylic acid MITSUBISHI GAS CHEMICAL CO (JP) 2011-08-31 EP disclosed
EP-2194037-A1 Process for producing a high purity aromatic polycarboxylic acid Mitsubishi Gas Chemical Company, Inc. (JP) 2010-06-09 EP disclosed
EP-1157981-B1 Process for producing a high purity aromatic polycarboxylic acid MITSUBISHI GAS CHEMICAL CO (JP) 2009-09-09 EP disclosed
US-7547803-B2 Process for producing a high purity aromatic polycarboxylic acid MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2009-06-16 US disclosed
US-20060058551-A1 Method of purifying aromatic polycarboxylic acid KOMATSU MAKOTO 2006-03-16 US disclosed
US-7005540-B2 Method of purifying aromatic polycarboxylic acid MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2006-02-28 US disclosed
EP-1389609-A1 METHOD OF PURIFYING AROMATIC POLYCARBOXYLIC ACID MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-02-18 EP disclosed
US-6642412-B2 Forming an amine salt of an aromatic polycarboxylic acid, continuously decomposing, removing the amine and water by distillation under heating, taking out a slurry, separating and recovering aromatic polycarboxylic acid crystals MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-11-04 US disclosed
US-20030055284-A1 Process for producing a high purity aromatic polycarboxylic acid SHIGEMATSU RYUSUKE (JP) 2003-03-20 US disclosed
US-6455731-B2 REACTING AROMATIC ACID WITH AMINE; SALT FROMATION; DECOMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2002-09-24 US disclosed
US-20020002305-A1 Process for producing a high purity aromatic polycarboxylic acid MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2002-01-03 US disclosed
EP-1157981-A2 Process for producing a high purity aromatic polycarboxylic acid MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-11-28 EP disclosed
US-5321182-A From naphthalene and polyethylbenzenes in the presence of an acid catalyst NIPPON STEEL CHEMICAL CO., LTD. (JP) 1994-06-14 US disclosed
EP-0494315-A1 PROCESS FOR PRODUCING 2-ALKYL-6-ETHYL-NAPHTHALENE NIPPON STEEL CHEMICAL CO., LTD. (JP) 1992-07-15 EP disclosed