Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 17/20 | 0.36 |
| ▸ | F2 | P00734 | 4/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2582321 | 0.83 | F12 (0.36) | F12F2 | |
| SCHEMBL7673571 | 0.82 | KCNH2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL27712072 | 0.81 | KCNH2 (0.33) | — | |
| Methylamine SCHEMBL28799881 | 0.78 | MTNR1A (0.33) | F12F2 | |
| SCHEMBL1917482 | 0.76 | BCHE (0.40) | F12F2BDKRB1 | |
| SCHEMBL224810 | 0.72 | F12 (0.36) | F12 | |
| SCHEMBL2172225 | 0.72 | F12 (0.36) | F12 | |
| SCHEMBL30290030 | 0.72 | F12 (0.36) | F12 | |
| SCHEMBL2172550 | 0.72 | F12 (0.36) | F12 | |
| SCHEMBL10812390 | 0.72 | F12 (0.36) | F12F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784671-A1 | DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY | XRad Therapeutics, Inc. (US) | 2021-03-03 | — | — | EP | disclosed |
| WO-2019201283-A1 | DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY | XRAD THERAPEUTICS, INC. (US) | 2019-10-24 | — | — | WO | disclosed |
| CN-101801194-A | Has 5-HT 63 ' the compound that replaces of receptor affinity | MEMORY PHARM CORP | 2010-08-11 | — | — | CN | disclosed |