Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122427 | 0.78 | KMT2A (0.57) | LMNACYP2D6CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL18269739 | 0.78 | KMT2A (0.38) | LMNAPOLBSMN1; SMN2KDM4EMAPT | |
| SCHEMBL8018700 | 0.75 | LMNA (0.50) | LMNAPOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22783909 | 0.72 | KMT2A (0.43) | LMNAPOLBSMN1; SMN2KDM4EMAPT | |
| SCHEMBL21696867 | 0.72 | KMT2A (0.53) | LMNACYP2D6CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL20014974 | 0.71 | POLB (0.50) | LMNAPOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL24886037 | 0.71 | CYP2D6 (0.58) | LMNAPOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL24886036 | 0.71 | HPGD (0.49) | LMNAPOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8013521 | 0.68 | CYP2D6 (0.63) | LMNAPOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL17608730 | 0.68 | RAB9A (0.61) | LMNAPOLBSMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11560394-B2 | Metal complex comprising amidine and indole fused cyclopentadienyl ligands | ARLANXEO NETHERLANDS B.V. | 2023-01-24 | — | — | US | disclosed |
| EP-3781582-A1 | METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS | Arlanxeo Netherlands B.V. (NL) | 2021-02-24 | — | — | EP | disclosed |
| CN-111989336-A | Metal complexes comprising amidine and indole fused cyclopentadienyl ligands | 阿朗新科荷兰有限公司 | 2020-11-24 | — | — | CN | disclosed |
| WO-2019203676-A1 | METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS | ARLANXEO NETHERLANDS B.V. (NL) | 2019-10-24 | — | — | WO | disclosed |
| WO-2019201838-A1 | METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS | ARLANXEO NETHERLANDS B.V. (NL) | 2019-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560394-B2 | Metal complex comprising amidine and indole fused cyclopentadienyl ligands | C5, C1S, CLIC4 | LMNA 1730/4885POLB 4475/4885CYP2D6 3518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.