Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17680609 | 0.81 | USP7 (0.41) | MAPTALDH1A1USP7 | |
| SCHEMBL28264564 | 0.81 | HTR2A (0.41) | HTR2ATAAR1 | |
| SCHEMBL24853040 | 0.80 | MTNR1A (0.45) | KDM4EUSP7TLR8 | |
| SCHEMBL543484 | 0.79 | ATM (0.40) | MAPTKDM4EALDH1A1USP7SMN1; SMN2 | |
| SCHEMBL24852679 | 0.78 | HDAC6 (0.45) | MAPTKDM4EALDH1A1TLR8NPSR1 | |
| SCHEMBL30006395 | 0.76 | ICMT (0.39) | ALDH1A1USP7TLR8 | |
| Hydrochloric Acid SCHEMBL3999224 | 0.75 | ADORA3 (0.44) | TLR8 | |
| SCHEMBL28786058 | 0.74 | TDP1 (0.47) | MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10933576 | 0.73 | CA12 (0.49) | ALDH1A1USP7 | |
| SCHEMBL24853045 | 0.73 | CYP4F2 (0.51) | MAPTKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781565-A1 | 2-METHYL-AZA-QUINAZOLINES | Bayer Pharma Aktiengesellschaft (DE) | 2021-02-24 | — | — | EP | disclosed |
| WO-2019201848-A1 | 2-METHYL-AZA-QUINAZOLINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-10-24 | — | — | WO | disclosed |