Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1421836 | 0.85 | SMN1; SMN2 (0.42) | ALDH1A1SMN1; SMN2LMNANPC1MAPK1 | |
| SCHEMBL13481260 | 0.85 | MAPT (0.40) | ALDH1A1SMN1; SMN2LMNARAB9AMAPT | |
| SCHEMBL10854375 | 0.82 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2LMNANPC1MAPK1 | |
| SCHEMBL9432871 | 0.82 | KDM4E (0.39) | ALDH1A1SMN1; SMN2LMNANPC1MAPK1 | |
| SCHEMBL12204057 | 0.80 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2LMNANPC1MAPK1 | |
| SCHEMBL8388439 | 0.80 | POLB (0.41) | ALDH1A1SMN1; SMN2LMNANPC1MAPK1 | |
| SCHEMBL23949976 | 0.79 | NUDT1 (0.51) | ALDH1A1SMN1; SMN2LMNAGRM5MAPT | |
| SCHEMBL30353321 | 0.79 | NUDT1 (0.51) | ALDH1A1SMN1; SMN2LMNAGRM5MAPT | |
| SCHEMBL13012202 | 0.79 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2LMNANPC1MAPK1 | |
| SCHEMBL1576783 | 0.78 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2LMNANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3870577-B1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2025-03-19 | — | — | EP | disclosed |
| US-20230109662-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2023-04-06 | — | — | US | disclosed |
| US-11541055-B2 | Inhibitors of human immunodeficiency virus replication | VIIV Healthcare UK (No.5) Limited (GB) | 2023-01-03 | — | — | US | disclosed |
| CN-113195475-A | Inhibitors of human immunodeficiency virus replication | VIIV保健英国第五有限公司 | 2021-07-30 | — | — | CN | disclosed |
| EP-3781565-A1 | 2-METHYL-AZA-QUINAZOLINES | Bayer Pharma Aktiengesellschaft (DE) | 2021-02-24 | — | — | EP | disclosed |
| US-20200360384-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2020-11-19 | — | — | US | disclosed |
| WO-2019201848-A1 | 2-METHYL-AZA-QUINAZOLINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11541055-B2 | Inhibitors of human immunodeficiency virus replication | EIF2AK2, POLR2E, POLR2H | ALDH1A1 2912/4885SMN1; SMN2 2896/4885LMNA 3667/4885 |
| US-20230109662-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | EIF2AK2, POLR2E, POLR2H | ALDH1A1 2912/4885SMN1; SMN2 2896/4885LMNA 3667/4885 |
| US-20200360384-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | EIF2AK2, POLR2E, POLR2H | ALDH1A1 2912/4885SMN1; SMN2 2896/4885LMNA 3667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.