Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24097335 | 1.00 | NOS3 (0.36) | NOS3NOS1NOS2MAPTTHRB | |
| SCHEMBL1397564 | 1.00 | NOS3 (0.36) | NOS3NOS1NOS2MAPTTHRB | |
| SCHEMBL29281259 | 0.86 | NOS3 (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL28247829 | 0.82 | TRIM24 (0.39) | NOS3NOS1NOS2TRIM24TRIM33 | |
| SCHEMBL22792768 | 0.78 | THRB (0.37) | MAPTTHRB | |
| SCHEMBL918723 | 0.77 | THRB (0.38) | MAPTTHRBTRIM24TRIM33ALDH1A1 | |
| SCHEMBL3973236 | 0.73 | NOS3 (0.36) | NOS3NOS1NOS2 | |
| SCHEMBL18535813 | 0.72 | KEAP1 (0.45) | ALDH1A1 | |
| SCHEMBL17247965 | 0.71 | SLC2A1 (0.40) | MAPTTHRBALDH1A1 | |
| SCHEMBL1711546 | 0.70 | MAPT (0.34) | NOS3NOS1NOS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4110298-A1 | HOT MELT EXTRUDED SOLID DISPERSIONS CONTAINING A BCL2 INHIBITOR | Guangzhou Lupeng Pharmaceutical Company Ltd. (CN) | 2023-01-04 | — | — | EP | disclosed |
| CN-113710812-A | Process for producing (1R,3R) -3- (trifluoromethyl) cyclohexan-1-ol and intermediate thereof | 株式会社API | 2021-11-26 | — | — | CN | disclosed |
| EP-3784654-A1 | ISOINDOLINES AS HDAC INHIBITORS | Valo Early Discovery, Inc. (US) | 2021-03-03 | — | — | EP | disclosed |
| WO-2020213731-A1 | METHOD FOR PRODUCING (1R,3R)-3-(TRIFLUOROMETHYL)CYCLOHEXAN-1-OL AND INTERMEDIATE THEREOF | 株式会社エーピーアイ コーポレーション | 2020-10-22 | — | — | WO | disclosed |
| WO-2019204550-A1 | ISOINDOLINES AS HDAC INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2019-10-24 | — | — | WO | disclosed |