Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21496866 | 1.00 | CHRNB2 (0.31) | CHRNB2CHRNA4KMT2AFDPS | |
| SCHEMBL21093109 | 0.77 | CA2 (0.34) | KMT2AFDPS | |
| SCHEMBL809706 | 0.77 | KMT2A (0.33) | CHRNB2CHRNA4KMT2AFDPS | |
| SCHEMBL16274044 | 0.77 | CA2 (0.34) | KMT2AFDPS | |
| SCHEMBL13247696 | 0.77 | KMT2A (0.33) | CHRNB2CHRNA4KMT2AFDPS | |
| SCHEMBL809853 | 0.77 | KMT2A (0.33) | CHRNB2CHRNA4KMT2AFDPS | |
| Hydrochloric Acid SCHEMBL4740768 | 0.75 | KMT2A (0.36) | CHRNB2CHRNA4KMT2AFDPS | |
| SCHEMBL8272557 | 0.75 | HCRTR2 (0.33) | KMT2AFDPS | |
| SCHEMBL21511644 | 0.73 | APLNR (0.36) | KMT2A | |
| SCHEMBL809421 | 0.72 | IDO1 (0.35) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019204505-A2 | K-RAS MODULATORS WITH A VINYL SULFONAMIDE MOIETY | THERAS, INC. (US) | 2019-10-24 | — | — | WO | disclosed |