SCHEMBL2149692

SCHEMBL2149692

c1ccc(-c2cc3cc4oc(-c5ccccc5)cc4cc3o2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.66
HDAC6 Q9UBN7 1/20 0.53
CYP3A4 P08684 3/20 0.52
HPGD P15428 3/20 0.52
AR P10275 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
ABCG2 Q9UNQ0 2/20 0.52
TP53 P04637 2/20 0.52
CYP19A1 P11511 2/20 0.52
CYP1B1 Q16678 2/20 0.52
GABRP O00591 1/20 0.52
GABRD O14764 1/20 0.52
CA12 O43570 1/20 0.52
TNKS O95271 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
ABCB1 P08183 1/20 0.52
PARP1 P09874 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15562420 0.96 MAOB (0.61) MAOBHDAC6CYP3A4HPGDAR
SCHEMBL23549921 0.96 MAOB (0.61) MAOBHDAC6CYP3A4HPGDAR
SCHEMBL20804736 0.96 MAOB (0.61) MAOBHDAC6CYP3A4HPGDAR
SCHEMBL25788793 0.92 MAOB (0.58) MAOBHDAC6CYP3A4HPGDAR
SCHEMBL24495227 0.92 MAOB (0.58) MAOBHDAC6CYP3A4HPGDAR
SCHEMBL23337583 0.89 MAOB (0.59) MAOBHDAC6CYP3A4HPGDAR
SCHEMBL12277935 0.87 MAOB (0.53) MAOBHDAC6CYP3A4HPGDAR
SCHEMBL30176902 0.86 MAPT (0.60) MAOBHDAC6CYP3A4HPGDAR
SCHEMBL28380621 0.86 MAPT (0.60) MAOBHDAC6CYP3A4HPGDAR
SCHEMBL14900925 0.85 MAOB (0.51) MAOBHDAC6CYP3A4HPGDAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220112996-A1 JEWELRY AND GEM STONE LIGHTING SYSTEMS AND APPARATUSES AND METHOD MAKING AND USING SAME ASHLEY PAUL (US) 2022-04-14 US disclosed
EP-3553151-A1 PHOSPHORESCENT SUBSTANCE AND PHOSPHORESCENT ELEMENT Kyushu University, National University Corporation (JP) 2019-10-16 EP disclosed
WO-2019189045-A1 PHOSPHORESCENT SUBSTANCE AND PHOSPHORESCENT ELEMENT 国立大学法人九州大学 2019-10-03 WO disclosed
US-20110166362-A1 NOVEL COMPOUND AND ORGANIC SEMICONDUCTOR MATERIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-07 US disclosed
EP-2341051-A1 NOVEL COMPOUND AND ORGANIC SEMICONDUCTOR MATERIAL Sumitomo Chemical Company, Limited (JP) 2011-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166362-A1 NOVEL COMPOUND AND ORGANIC SEMICONDUCTOR MATERIAL SCLY, MSRB3, SOD1 MAOB 180/4885HDAC6 1960/4885CYP3A4 412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.