Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21458258 | 0.85 | CCR5 (0.38) | YTHDC1DPP8DPP7NPSR1MEN1 | |
| SCHEMBL1963929 | 0.81 | CCR5 (0.41) | YTHDC1DPP8DPP7NPSR1MEN1 | |
| SCHEMBL25572115 | 0.76 | NPSR1 (0.44) | YTHDC1DPP8DPP7NPSR1MEN1 | |
| SCHEMBL21481659 | 0.76 | CCR5 (0.40) | YTHDC1DPP8DPP7NPSR1MEN1 | |
| SCHEMBL21506715 | 0.76 | YTHDC1 (0.39) | YTHDC1DPP8DPP7NPSR1MEN1 | |
| SCHEMBL31266684 | 0.75 | YTHDC1 (0.41) | YTHDC1DPP8DPP7NPSR1MEN1 | |
| SCHEMBL31187320 | 0.74 | MEN1 (0.43) | YTHDC1DPP8DPP7NPSR1MEN1 | |
| SCHEMBL21228012 | 0.73 | YTHDC1 (0.42) | YTHDC1DPP8DPP7NPSR1MEN1 | |
| SCHEMBL26361725 | 0.73 | YTHDC1 (0.43) | YTHDC1DPP8DPP7NPSR1MEN1 | |
| SCHEMBL18987888 | 0.72 | ALDH1A1 (0.42) | YTHDC1DPP8DPP7NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781550-A1 | BICYCLIC CARBOXAMIDES AND METHODS OF USE THEREOF | Tempest Therapeutics, Inc. (US) | 2021-02-24 | — | — | EP | disclosed |
| WO-2019204523-A1 | BICYCLIC CARBOXAMIDES AND METHODS OF USE THEREOF | TEMPEST THERAPEUTICS, INC. (US) | 2019-10-24 | — | — | WO | disclosed |