Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10349652 | 0.87 | PDE10A (0.40) | KDM4EALDH1A1PDE10AGSK3BRPS6KB1 | |
| Hydrochloric Acid SCHEMBL10382640 | 0.86 | GSK3B (0.40) | KDM4EALDH1A1PDE10AGSK3BRPS6KB1 | |
| SCHEMBL19629766 | 0.79 | PDE10A (0.38) | KDM4EPDE10AGSK3BMEN1KMT2A | |
| SCHEMBL11707727 | 0.79 | OPRD1 (0.37) | KDM4EALDH1A1PDE10AGSK3BRPS6KB1 | |
| SCHEMBL2908444 | 0.75 | PDE10A (0.45) | KDM4EALDH1A1PDE10AGSK3BRPS6KB1 | |
| SCHEMBL90572 | 0.75 | PDE10A (0.45) | KDM4EALDH1A1PDE10AGSK3BRPS6KB1 | |
| SCHEMBL2910280 | 0.75 | PDE10A (0.45) | KDM4EALDH1A1PDE10AGSK3BRPS6KB1 | |
| SCHEMBL21831322 | 0.74 | HRH3 (0.47) | KDM4ESLC6A2ADRA1AHTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL27510131 | 0.73 | GSK3B (0.45) | KDM4EALDH1A1PDE10AGSK3BRPS6KB1 | |
| Hydrochloric Acid SCHEMBL10626673 | 0.73 | GSK3B (0.45) | KDM4EALDH1A1PDE10AGSK3BRPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450318-B2 | CXCR4 receptor antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450318-B2 | CXCR4 receptor antagonists | CXCR4, CXCR1, CXCR2 | KDM4E 4172/4885ALDH1A1 856/4885PDE10A 583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.