Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | RORC | P51449 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4247052 | 0.86 | NPC1 (0.86) | NPC1RAB9APTPN1HDAC2HDAC8 | |
| SCHEMBL13601058 | 0.84 | LMNA (0.78) | NPC1RAB9AHDAC2HDAC8HDAC6 | |
| SCHEMBL9114835 | 0.83 | PTGS1 (0.77) | NPC1RAB9ALMNAMEN1POLB | |
| SCHEMBL1315526 | 0.83 | PTPN1 (0.87) | NPC1RAB9APTPN1HDAC2HDAC8 | |
| SCHEMBL14715847 | 0.81 | PTPN1 (0.84) | NPC1RAB9APTPN1HDAC2HDAC8 | |
| N-Phenylbenzamide SCHEMBL5586411 | 0.80 | NPC1 (0.71) | NPC1RAB9APTPN1HDAC2HDAC8 | |
| SCHEMBL19501818 | 0.80 | RAB9A (0.81) | NPC1RAB9ALMNAMEN1POLB | |
| SCHEMBL12010918 | 0.80 | RAB9A (0.81) | NPC1RAB9ALMNAMEN1POLB | |
| SCHEMBL17115744 | 0.80 | NPC1 (0.81) | NPC1RAB9ALMNAMEN1POLB | |
| SCHEMBL26953087 | 0.79 | PTPN1 (0.88) | NPC1RAB9APTPN1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450265-B2 | Method for producing amides or polyamides by using aromatic carbamates by way of isocyanates as precursors through catalyzed thermal processes and method for producing aromatic carbamate precursors from aromatic amines | GREAT EASTERN RESINS INDUSTRIAL CO., LTD. (TW) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450265-B2 | Method for producing amides or polyamides by using aromatic carbamates by way of isocyanates as precursors through catalyzed thermal processes and method for producing aromatic carbamate precursors from aromatic amines | NAAA, NISCH, CPS1 | NPC1 2925/4885RAB9A 3109/4885PTPN1 3790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.