Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.75 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.75 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.75 |
| ▸ | USP2 | O75604 | 1/20 | 0.75 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.75 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | ACE | P12821 | 1/20 | 0.75 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.75 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.75 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.75 |
| ▸ | PDE4A | P27815 | 1/20 | 0.75 |
| ▸ | HTR2A | P28223 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24490915 | 0.92 | PPARG (0.74) | PPARGAGTR1KDM4EABCC3ABCC4 | |
| SCHEMBL8268211 | 0.90 | PPARG (0.80) | PPARGAGTR1KDM4EABCC3ABCC4 | |
| SCHEMBL809909 | 0.88 | PPARG (0.78) | PPARGAGTR1KDM4EABCC3ABCC4 | |
| SCHEMBL12664495 | 0.88 | PPARG (0.77) | PPARGAGTR1KDM4EABCC3ABCC4 | |
| SCHEMBL1249733 | 0.87 | PPARG (0.76) | PPARGAGTR1KDM4EABCC3ABCC4 | |
| SCHEMBL1249891 | 0.87 | PPARG (0.76) | PPARGAGTR1KDM4EABCC3ABCC4 | |
| SCHEMBL9091775 | 0.87 | PPARG (0.78) | PPARGAGTR1KDM4EABCC3ABCC4 | |
| SCHEMBL1249924 | 0.87 | PPARG (0.78) | PPARGAGTR1KDM4EABCC3ABCC4 | |
| SCHEMBL13382771 | 0.87 | PPARG (0.75) | PPARGAGTR1KDM4EABCC3ABCC4 | |
| SCHEMBL17946015 | 0.86 | PPARG (0.88) | PPARGAGTR1KDM4EABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450280-B2 | Tetrazolones as a carboxylic acid bioisosteres | RIGEL PHARMACEUTICALS, INC. (US) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450280-B2 | Tetrazolones as a carboxylic acid bioisosteres | GLS, CYP11B2, GLS2 | PPARG 75/4885AGTR1 877/4885KDM4E 4668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.