Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | DHODH | Q02127 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21468503 | 0.88 | ALDH1A1 (0.64) | ALDH1A1MAPTSMN1; SMN2LMNADHODH | |
| SCHEMBL21499368 | 0.88 | ALDH1A1 (0.59) | ALDH1A1MAPTSMN1; SMN2LMNADHODH | |
| SCHEMBL21499312 | 0.83 | MAPT (0.58) | ALDH1A1MAPTSMN1; SMN2LMNADHODH | |
| SCHEMBL21499358 | 0.82 | MAPT (0.57) | ALDH1A1MAPTSMN1; SMN2LMNADHODH | |
| SCHEMBL21499332 | 0.82 | LMNA (0.58) | ALDH1A1MAPTSMN1; SMN2LMNADHODH | |
| SCHEMBL21499314 | 0.81 | MAPT (0.56) | ALDH1A1MAPTSMN1; SMN2LMNADHODH | |
| SCHEMBL21468548 | 0.81 | MAPT (0.76) | ALDH1A1MAPTSMN1; SMN2LMNADHODH | |
| SCHEMBL21499319 | 0.81 | MAPT (0.55) | ALDH1A1MAPTSMN1; SMN2LMNADHODH | |
| SCHEMBL21499328 | 0.81 | MAPT (0.61) | ALDH1A1MAPTSMN1; SMN2LMNADHODH | |
| SCHEMBL21499394 | 0.81 | MAPT (0.64) | ALDH1A1MAPTSMN1; SMN2LMNADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450263-B2 | Benzo annulenes as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450263-B2 | Benzo annulenes as antiviral agents | MAVS, ZC3HAV1, GABBR1 | ALDH1A1 187/4885MAPT 760/4885SMN1; SMN2 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.