SCHEMBL21499751

SCHEMBL21499751

O=Cc1cc(OC(=O)c2ccc(O)cc2)ccc1O

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 9/20 0.54
NR1H4 Q96RI1 2/20 0.46
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
TRIM24 O15164 1/20 0.42
TYR P14679 1/20 0.42
TRIM33 Q9UPN9 1/20 0.42
SENP1 Q9P0U3 1/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GABRA3 P34903 1/20 0.41
GABRA2 P47869 1/20 0.41
GABRB2 P47870 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21511144 0.91 ERN1 (0.54) ERN1NR1H4CA1CA2MEN1
SCHEMBL7030208 0.88 KMT2A (0.57) ERN1CA2MEN1MAPTKMT2A
SCHEMBL21499770 0.79 ESR1 (0.50) ERN1TRIM24TYRTRIM33MEN1
SCHEMBL3887594 0.78 ERN1 (0.62) ERN1TRIM24TYRTRIM33MEN1
SCHEMBL28147777 0.78 NSD2 (0.57) ERN1TRIM24TRIM33MEN1MAPT
SCHEMBL2727720 0.78 KMT2A (0.57) CA2TRIM24TYRTRIM33MEN1
SCHEMBL777824 0.78 KMT2A (0.65) CA1CA2SENP1MEN1MAPT
SCHEMBL767555 0.78 NR1H4 (0.55) NR1H4CA1CA2SENP1MEN1
SCHEMBL766699 0.78 ESR1 (0.50) NR1H4CA1CA2SENP1MEN1
SCHEMBL767381 0.78 NR1H4 (0.48) NR1H4CA1CA2SENP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200283399-A1 METHOD OF PRODUCING POLYMERIZABLE COMPOUND, AND SOLUTION OF POLYMERIZABLE COMPOUND ZEON CORPORATION (JP) 2020-09-10 US disclosed
EP-3604289-A1 POLYMERIZABLE COMPOUND PRODUCTION METHOD AND POLYMERIZABLE COMPOUND SOLUTION Zeon Corporation (JP) 2020-02-05 EP disclosed
US-20190322872-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICAL FILM, OPTICALLY ANISOTROPIC BODY, POLARIZER, FLAT PANEL DISPLAY, ORGANIC ELECTROLUMINESCENCE DISPLAY, ANTIREFLECTION FILM, AND COMPOUND ZEON CORPORATION (JP) 2019-10-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190322872-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICAL FILM, OPTICALLY ANISOTROPIC BODY, POLARIZER, FLAT PANEL DISPLAY, ORGANIC ELECTROLUMINESCENCE DISPLAY, ANTIREFLECTION FILM, AND COMPOUND H1-0, H1-4, H1-10 ERN1 3024/4885NR1H4 517/4885CA1 2425/4885
US-20200283399-A1 METHOD OF PRODUCING POLYMERIZABLE COMPOUND, AND SOLUTION OF POLYMERIZABLE COMPOUND PDE8A, ADCY6, TKFC ERN1 1631/4885NR1H4 4152/4885CA1 1325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.