Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14451670 | 0.87 | MIF (0.52) | ESR1ESR2NR1H4MAPTKMT2A | |
| SCHEMBL13021276 | 0.87 | NR1H4 (0.46) | ESR1ESR2NR1H4MAPTKMT2A | |
| SCHEMBL29653765 | 0.83 | SENP1 (0.46) | ESR1ESR2KMT2ASENP1MEN1 | |
| SCHEMBL777824 | 0.80 | KMT2A (0.65) | ESR1ESR2MAPTKMT2ASENP1 | |
| SCHEMBL13223171 | 0.80 | KMT2A (0.49) | ESR1ESR2MAPTKMT2AMEN1 | |
| SCHEMBL767555 | 0.80 | NR1H4 (0.55) | ESR1ESR2NR1H4MAPTKMT2A | |
| SCHEMBL767381 | 0.80 | NR1H4 (0.48) | ESR1ESR2NR1H4MAPTKMT2A | |
| SCHEMBL15014179 | 0.80 | APP (0.46) | ESR1ESR2NR1H4MAPTKMT2A | |
| SCHEMBL688276 | 0.80 | HSD17B10 (0.59) | ESR1ESR2MAPTKMT2ASENP1 | |
| SCHEMBL740606 | 0.80 | HSD17B10 (0.59) | ESR1ESR2MAPTKMT2ASENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404794-B2 | Liquid crystal compositions | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-03-26 | — | — | US | disclosed |
| US-8344175-B2 | Liquid crystal compositions, polymer networks derived therefrom and process for making the same | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-01 | — | — | US | disclosed |
| US-20120104316-A1 | LIQUID CRYSTAL COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-05-03 | — | — | US | disclosed |
| EP-2440631-A1 | LIQUID CRYSTAL COMPOSITIONS | E. I. du Pont de Nemours and Company (US) | 2012-04-18 | — | — | EP | disclosed |
| US-20120068116-A1 | LIQUID CRYSTAL COMPOSITIONS | E.I.DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-22 | — | — | US | disclosed |
| US-20120071618-A1 | LIQUID CRYSTAL COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-22 | — | — | US | disclosed |
| US-8067068-B2 | Liquid crystal compositions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-29 | — | — | US | disclosed |
| US-8044228-B2 | Liquid crystal compositions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-10-25 | — | — | US | disclosed |
| US-8034255-B2 | Liquid crystal compositions | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-10-11 | — | — | US | disclosed |
| US-20110114885-A1 | LIQUID CRYSTAL COMPOSITIONS, POLYMER NETWORKS DERIVED THEREFROM AND PROCESS FOR MAKING THE SAME | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-19 | — | — | US | disclosed |
| EP-2001974-B1 | LIQUID CRYSTAL COMPOSITIONS, POLYMER NETWORKS DERIVED THEREFROM AND PROCESS FOR MAKING THE SAME | DU PONT (US) | 2011-03-30 | — | — | EP | disclosed |
| US-7879256-B2 | bis(meth)acrylates with esters linking mesogen to a flexible spacer and polymerizable (meth)acrylates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-01 | — | — | US | disclosed |
| WO-2010144411-A1 | LIQUID CRYSTAL COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-16 | — | — | WO | disclosed |
| US-20100308269-A1 | LIQUID CRYSTAL COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100308268-A1 | LIQUID CRYSTAL COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100308265-A1 | LIQUID CRYSTAL COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100308270-A1 | LIQUID CRYSTAL COMPOSTIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
| EP-2001974-A1 | LIQUID CRYSTAL COMPOSITIONS, POLYMER NETWORKS DERIVED THEREFROM AND PROCESS FOR MAKING THE SAME | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007120458-A1 | LIQUID CRYSTAL COMPOSITIONS, POLYMER NETWORKS DERIVED THEREFROM AND PROCESS FOR MAKING THE SAME | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-10-25 | — | — | WO | disclosed |
| US-20070228326-A1 | Liquid crystal compositions, polymer networks derived therefrom and process for making the same | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100308265-A1 | LIQUID CRYSTAL COMPOSITIONS | CNOT9, AQP3, AQP1 | ESR1 3933/4885ESR2 4550/4885NR1H4 4058/4885 |
| US-20100308270-A1 | LIQUID CRYSTAL COMPOSTIONS | TTR, CNOT9, CNOT7 | ESR1 3907/4885ESR2 4588/4885NR1H4 3771/4885 |
| US-20120068116-A1 | LIQUID CRYSTAL COMPOSITIONS | AQP3, AQP1, NCAPD2 | ESR1 3666/4885ESR2 4111/4885NR1H4 2923/4885 |
| US-20120071618-A1 | LIQUID CRYSTAL COMPOSITIONS | CNOT9, AQP3, AQP1 | ESR1 3933/4885ESR2 4550/4885NR1H4 4058/4885 |
| US-20110114885-A1 | LIQUID CRYSTAL COMPOSITIONS, POLYMER NETWORKS DERIVED THEREFROM AND PROCESS FOR MAKING THE SAME | THEM6, NOTUM, WEE1 | ESR1 3921/4885ESR2 4621/4885NR1H4 3605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.