Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ULK1 | O75385 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | UBE2M | P61081 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12144664 | 0.74 | EPHX2 (0.57) | EPHX2CA12CA1CA2CA9 | |
| SCHEMBL1847415 | 0.74 | EPHX2 (0.58) | EPHX2CA12CA1CA2CA9 | |
| SCHEMBL440957 | 0.72 | LMNA (0.59) | EPHX2CA12CA1CA2CA9 | |
| SCHEMBL20560615 | 0.71 | EPHX2 (0.56) | EPHX2CA12CA1CA2CA9 | |
| SCHEMBL30499689 | 0.71 | CA12 (0.57) | EPHX2CA12CA1CA2CA9 | |
| SCHEMBL2755849 | 0.71 | CA12 (0.57) | EPHX2CA12CA1CA2CA9 | |
| SCHEMBL20560640 | 0.71 | EPHX2 (0.49) | EPHX2CA12CA1CA2CA9 | |
| SCHEMBL11404399 | 0.71 | EPHX2 (0.48) | EPHX2CA12CA1CA2CA9 | |
| SCHEMBL3872255 | 0.71 | EPHX2 (0.46) | EPHX2CA12CA1CA2CA9 | |
| SCHEMBL31646292 | 0.71 | EPHX2 (0.46) | EPHX2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019204816-A1 | IMIDAZOPYRIDINES USEFUL AS MITOCHONDRIAL UNCOUPLERS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2019-10-24 | — | — | WO | disclosed |