Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ULK1 | O75385 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3872255 | 1.00 | EPHX2 (0.46) | EPHX2ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL25004728 | 0.86 | MAPT (0.38) | EPHX2ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL19532816 | 0.83 | CA2 (0.41) | EPHX2ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL31757635 | 0.81 | APP (0.39) | EPHX2ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL880789 | 0.80 | ALDH1A1 (0.59) | ALDH1A1POLBTDP1L3MBTL1CYP1A2 | |
| SCHEMBL20620245 | 0.80 | EPHX2 (0.43) | EPHX2ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL23591206 | 0.80 | SOS1 (0.36) | EPHX2POLBULK1CA12CA1 | |
| SCHEMBL5514195 | 0.79 | MAPT (0.44) | ALDH1A1POLBTDP1L3MBTL1EGFR | |
| SCHEMBL9229491 | 0.79 | TAS2R14 (0.53) | ALDH1A1POLBTDP1L3MBTL1CYP1A2 | |
| SCHEMBL11404399 | 0.79 | EPHX2 (0.48) | EPHX2ALDH1A1POLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025133915-A1 | COMPOUNDS WHICH BIND TO PNPLA3I148M AND THEIR USE TO TREAT LIVER DISEASES | NOVARTIS AG (CH) | 2025-06-26 | — | — | WO | disclosed |