SCHEMBL2150130

SCHEMBL2150130

CCCCC(CC)COP(Oc1ccc(C)cc1)Oc1ccc(C)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.40
CYP3A4 P08684 5/20 0.40
CA2 P00918 1/20 0.40
TDP1 Q9NUW8 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
LMNA P02545 3/20 0.37
TSHR P16473 3/20 0.36
MAPK1 P28482 3/20 0.36
HSD17B10 Q99714 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
ATM Q13315 1/20 0.36
PTGES O14684 1/20 0.35
ALOX5 P09917 1/20 0.35
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL269427 0.87 ALDH1A1 (0.48) ALDH1A1CYP3A4CA2TDP1L3MBTL1
SCHEMBL21436765 0.85 ALDH1A1 (0.47) ALDH1A1CYP3A4CA2TDP1L3MBTL1
SCHEMBL4011150 0.84 ALDH1A1 (0.48) ALDH1A1CYP3A4CA2TDP1L3MBTL1
SCHEMBL28646685 0.83 ALDH1A1 (0.48) ALDH1A1CYP3A4CA2TDP1L3MBTL1
SCHEMBL11236714 0.82 LMNA (0.38) ALDH1A1CYP3A4CA2TDP1L3MBTL1
SCHEMBL5530604 0.81 S1PR1 (0.42) ALDH1A1CYP3A4CA2LMNAMAPK1
SCHEMBL9070060 0.81 S1PR1 (0.42) ALDH1A1CYP3A4CA2LMNAMAPK1
SCHEMBL762244 0.80 CYP3A4 (0.45) ALDH1A1CYP3A4CA2TDP1L3MBTL1
SCHEMBL19924884 0.78 PRSS1 (0.40) ALDH1A1CYP3A4CA2L3MBTL1LMNA
SCHEMBL2150871 0.77 MITF (0.39) ALDH1A1CYP3A4L3MBTL1LMNAPTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8680184-B2 Curable composition and cured product thereof KANEKA CORPORATION (JP) 2014-03-25 US disclosed
EP-2341106-B1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF KANEKA CORP (JP) 2013-05-29 EP disclosed
US-20110213058-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF KANEKA CORPORATION (JP) 2011-09-01 US disclosed
EP-2341106-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF Kaneka Corporation (JP) 2011-07-06 EP disclosed
US-4557618-A PHENOLIC DEVELOPER AND ELECTRON DONATING COLORLESS DYE; DESENSITIZING COMPOUND PENTEL KABUSHIKI KAISHA (JP) 1985-12-10 US disclosed
US-4255321-A BLENDS WITH HIGH IMPACT-STRENGTH BUTADIENE-STYRENE COPOLYMER INCLUDE A SYNERGISTIC MIXTURE OF A METAL SULFIDE AND ZINC OXIDE; ENGINEERING THERMOPLASTICS GENERAL ELECTRIC COMPANY (US) 1981-03-10 US disclosed
US-4123474-A STABILIZED THERMOPLASTIC MOLDING MATERIAL GENERAL ELECTRIC COMPANY (US) 1978-10-31 US disclosed