Iodide

Iodide

SCHEMBL2150737

FCc1ccccn1.I

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2216286 0.97
SCHEMBL29901546 0.97
Bromide SCHEMBL28499361 0.95
Iodide SCHEMBL14798201 0.89 HRH1 (0.44)
Iodide SCHEMBL14798203 0.89 HRH1 (0.44)
SCHEMBL28194856 0.78
SCHEMBL14141541 0.78 HRH1 (0.42)
SCHEMBL230753 0.76 HRH1 (0.73)
SCHEMBL29830938 0.76 L3MBTL1 (0.59)
SCHEMBL41191 0.76 L3MBTL1 (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2763539-B1 ANTIBACTERIAL COMPOUNDS GLAXO GROUP LTD (GB) 2017-02-08 EP disclosed
US-9340556-B2 Antibacterial compounds GLAXO GROUP LIMITED (GB) 2016-05-17 US disclosed
US-9238657-B2 Cephalosporin having catechol group SHIONOGI & CO., LTD. (JP) 2016-01-19 US disclosed
EP-2341053-B1 CEPHALOSPORIN HAVING CATECHOL GROUP SHIONOGI & CO (JP) 2016-01-13 EP disclosed
US-20150344502-A1 CEPHEM COMPOUND SHIONOGI & CO., LTD. (JP) 2015-12-03 US disclosed
US-9145425-B2 Cephem compound having catechol group SHIONOGI & CO., LTD. (JP) 2015-09-29 US disclosed
US-9085589-B2 Cephem derivative SHIONOGI & CO., LTD. (JP) 2015-07-21 US disclosed
US-8883773-B2 Cephem compound having pseudo-catechol group SHIONOGI & CO., LTD. (JP) 2014-11-11 US disclosed
US-20140249126-A1 ANTIBACTERIAL COMPOUNDS GLAXO GROUP LIMITED (GB) 2014-09-04 US disclosed
EP-2763539-A1 ANTIBACTERIAL COMPOUNDS Glaxo Group Limited (GB) 2014-08-13 EP disclosed
US-20130102583-A1 CEPHEM COMPOUND HAVING CATECHOL GROUP SHIONOGI & CO., LTD. (JP) 2013-04-25 US disclosed
US-20130096299-A1 NOVEL CEPHEM DERIVATIVE SHIONOGI & CO., LTD. (JP) 2013-04-18 US disclosed
WO-2013052568-A1 ANTIBACTERIAL COMPOUNDS GLAXO GROUP LIMITED (GB) 2013-04-11 WO disclosed
US-20130079319-A1 CEPHEM COMPOUND HAVING PSEUDO-CATECHOL GROUP SHIONOGI & CO., LTD. (JP) 2013-03-28 US disclosed
EP-2557082-A1 CEPHEM COMPOUND HAVING CATECHOL GROUP Shionogi & Co., Ltd. (JP) 2013-02-13 EP disclosed
US-20110190254-A1 CEPHALOSPORIN HAVING CATECHOL GROUP SHIONOGI & CO., LTD. (JP) 2011-08-04 US disclosed
EP-2341053-A1 CEPHALOSPORIN HAVING CATECHOL GROUP Shionogi & Co., Ltd. (JP) 2011-07-06 EP disclosed