SCHEMBL2151024

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2150969	0.99	HTR2B (0.44)	HTR2BAKR1C3CA12CA1CA2
	SCHEMBL15576264	0.88	HTR2B (0.52)	HTR2BAKR1C3KMT2AMEN1KDM4E
	SCHEMBL15576256	0.87	HTR2B (0.53)	HTR2BAKR1C3KMT2AMEN1KDM4E
	SCHEMBL2151202	0.85	CA12 (0.41)	HTR2BAKR1C3CA12CA1CA2
	SCHEMBL2150646	0.84	CA12 (0.40)	HTR2BAKR1C3CA12CA1CA2
	SCHEMBL2178511	0.79	CA1 (0.40)	HTR2BCA1CA2KDM4EBRD4
	SCHEMBL3134393	0.78	HTR2B (0.39)	HTR2BCA1CA2KDM4EBRD4
	SCHEMBL13379526	0.75	PRMT6 (0.40)	—
	SCHEMBL2150740	0.75	HTR6 (0.44)	HTR7
	SCHEMBL2151226	0.75	MEN1 (0.48)	AKR1C3CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.