SCHEMBL21515293

SCHEMBL21515293

c1ccc2c(c1)Cc1ccc(-c3nc(-c4ccccc4N4c5ccc6ccccc6c5-c5cccc6cccc4c56)nc4ccccc34)cc1-2

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 1/20 0.32
PDK2 Q15119 1/20 0.32
PDK3 Q15120 1/20 0.32
PDK4 Q16654 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
PKM P14618 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
CYP2C19 P33261 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22944755 0.82 PDE6D (0.31) PDK1PDK2PDK3PDK4MEN1
SCHEMBL21515289 0.81 PDE6D (0.32) KDM4EPDE6DATM
SCHEMBL22944786 0.79 MAPT (0.35) MEN1KMT2AKDM4ENPC1TP53
SCHEMBL22944734 0.78 PDE6D (0.31) MEN1KMT2APDE6DATM
SCHEMBL21515279 0.74 METAP1 (0.39) MEN1KMT2AKDM4ENPC1TP53
SCHEMBL26736749 0.73 L3MBTL1 (0.41) MEN1KMT2AKDM4ENPC1MAPT
SCHEMBL21515396 0.72 PDE6D (0.40) MEN1KMT2AKDM4ENPC1MAPT
SCHEMBL22945113 0.72 ALDH1A1 (0.40) MEN1KMT2AKDM4ENPC1MAPT
SCHEMBL21515405 0.72 CYP1A2 (0.39) MEN1KMT2ANPC1MAPTTSHR
SCHEMBL21515434 0.72 PRKDC (0.35) MEN1KMT2AMAPTPDE6DATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019203613-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 2019-10-24 WO disclosed