SCHEMBL22944786

SCHEMBL22944786

c1ccc2cc(N3c4ccc5ccccc5c4-c4cccc5cccc3c45)c(-c3nc(-c4ccncc4)c4ccccc4n3)cc2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.35
KDM4E B2RXH2 6/20 0.35
HPGD P15428 4/20 0.35
ALDH1A1 P00352 3/20 0.35
LMNA P02545 5/20 0.35
MAPK1 P28482 2/20 0.35
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 4/20 0.32
KMT2A Q03164 4/20 0.32
ATM Q13315 1/20 0.32
MAPK8 P45983 1/20 0.32
MAPK9 P45984 1/20 0.32
MAPK10 P53779 1/20 0.32
MAPK11 Q15759 2/20 0.32
MAPK14 Q16539 2/20 0.32
USP2 O75604 2/20 0.32
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22945113 0.84 ALDH1A1 (0.40) MAPTKDM4EHPGDALDH1A1LMNA
SCHEMBL21515288 0.83 ADORA2A (0.38) MAPTKDM4EHPGDALDH1A1LMNA
SCHEMBL22944754 0.83
SCHEMBL22945345 0.80 PDE6D (0.36) MAPTKDM4EHPGDALDH1A1LMNA
SCHEMBL22945335 0.79 ALDH1A1 (0.40) MAPTKDM4EHPGDALDH1A1LMNA
SCHEMBL21515293 0.79 PDK1 (0.32) MAPTKDM4EMAPK1NPC1RAB9A
SCHEMBL21515381 0.79 CYP1A2 (0.36) MAPTHPGDALDH1A1MAPK1NPC1
SCHEMBL21515279 0.78 METAP1 (0.39) MAPTKDM4EHPGDALDH1A1LMNA
SCHEMBL21515396 0.76 PDE6D (0.40) MAPTKDM4EHPGDALDH1A1LMNA
SCHEMBL21515473 0.76 PDE6D (0.38) MAPTKDM4EHPGDALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2021-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME DRD1, DRD3, DRD2 MAPT 2771/4885KDM4E 1857/4885HPGD 2943/4885
US-11812658-B2 Compound and organic light emitting diode comprising same DRD1, DRD3, DRD2 MAPT 2771/4885KDM4E 1857/4885HPGD 2943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.