Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28170660 | 0.86 | KMT2A (0.44) | KMT2ANUDT1TLR8 | |
| SCHEMBL28170602 | 0.78 | KMT2A (0.44) | KMT2AHTR2CHTR2BTAAR1ADRA2A | |
| SCHEMBL13269009 | 0.73 | PDPK1 (0.49) | LMNAHIF1ANUDT1ALDH1A1ADORA2A | |
| SCHEMBL13268764 | 0.73 | HTR2C (0.37) | KMT2AHTR2CHTR2BLMNAKDM4E | |
| SCHEMBL13268765 | 0.73 | PDPK1 (0.49) | LMNAHIF1ANUDT1ALDH1A1ADORA2A | |
| SCHEMBL13269007 | 0.73 | HTR2C (0.37) | KMT2AHTR2CHTR2BLMNAKDM4E | |
| SCHEMBL27966111 | 0.73 | KMT2A (0.40) | KMT2AHTR2CHTR2BTAAR1NUDT1 | |
| SCHEMBL10353058 | 0.72 | HTR2C (0.40) | KMT2AHTR2CHTR2BTAAR1LMNA | |
| SCHEMBL2033897 | 0.70 | KMT2A (0.41) | KMT2AHTR2CHTR2BTAAR1ADRA2A | |
| SCHEMBL11010898 | 0.70 | GAA (0.43) | KMT2AHTR2CHTR2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3960729-A1 | COMPOUNDS AND METHODS OF TREATING INFECTIONS | Neoculi Pty Ltd (AU) | 2022-03-02 | — | — | EP | claimed |
| US-10562880-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD. (AU) | 2020-02-18 | — | — | US | claimed |
| US-20190330178-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2019-10-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330178-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | KMT2A 2912/4885HTR2C 3345/4885HTR2B 4278/4885 |
| US-10562880-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | KMT2A 2912/4885HTR2C 3345/4885HTR2B 4278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.