Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27966111 | 0.89 | KMT2A (0.40) | KMT2ABACE1MPOHTR2CHTR2B | |
| SCHEMBL22423878 | 0.82 | KMT2A (0.46) | KMT2ABACE1MPONUDT1TYR | |
| SCHEMBL2033897 | 0.79 | KMT2A (0.41) | KMT2AMPOHTR2CHTR2BNUDT1 | |
| SCHEMBL21522497 | 0.78 | KMT2A (0.43) | KMT2AHTR2CHTR2BNUDT1TAAR1 | |
| SCHEMBL28849339 | 0.76 | NUDT1 (0.43) | KMT2ABACE1MPOHTR2CHTR2B | |
| SCHEMBL22423864 | 0.74 | TYR (0.41) | KMT2ABACE1MPONUDT1TYR | |
| SCHEMBL10353058 | 0.73 | HTR2C (0.40) | KMT2AHTR2CHTR2BTYRNPC1 | |
| SCHEMBL11010898 | 0.72 | GAA (0.43) | KMT2AMPOHTR2CHTR2B | |
| SCHEMBL10399424 | 0.71 | NOS2 (0.48) | RAB9AADORA2AADORA1 | |
| SCHEMBL8989811 | 0.71 | KMT2A (0.43) | KMT2AHTR2CTAAR1ADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107106524-A | Methods for treating protozoal infections | 尼奥酷里私人有限公司 | 2017-08-29 | — | — | CN | claimed |