SCHEMBL21523239

SCHEMBL21523239

C=CC[C](CC=C)CCCCCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.48
FAAH O00519 1/20 0.47
CES2 O00748 3/20 0.42
CES1 P23141 3/20 0.42
GPR84 Q9NQS5 7/20 0.41
PPARG P37231 7/20 0.41
PPARD Q03181 7/20 0.41
PPARA Q07869 7/20 0.41
HDAC11 Q96DB2 5/20 0.41
PTPN1 P18031 3/20 0.41
ALDH1A1 P00352 3/20 0.41
TLR2 O60603 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
FABP4 P15090 2/20 0.41
SLC22A6 Q4U2R8 1/20 0.41
SLC22A8 Q8TCC7 1/20 0.41
MEN1 O00255 1/20 0.41
ESR1 P03372 1/20 0.41
ALOX15 P16050 1/20 0.41
PDE4A P27815 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11357097 1.00 TSHR (0.48) TSHRFAAHCES2CES1GPR84
SCHEMBL21523236 1.00 TSHR (0.48) TSHRFAAHCES2CES1GPR84
SCHEMBL21523241 1.00 TSHR (0.48) TSHRFAAHCES2CES1GPR84
SCHEMBL21523252 1.00 TSHR (0.48) TSHRFAAHCES2CES1GPR84
SCHEMBL21523250 1.00 TSHR (0.48) TSHRFAAHCES2CES1GPR84
SCHEMBL21523249 1.00 TSHR (0.48) TSHRFAAHCES2CES1GPR84
SCHEMBL21523258 1.00 TSHR (0.48) TSHRFAAHCES2CES1GPR84
SCHEMBL21523240 1.00 TSHR (0.48) TSHRFAAHCES2CES1GPR84
SCHEMBL21523257 1.00 TSHR (0.48) TSHRFAAHCES2CES1GPR84
SCHEMBL8670724 1.00 TSHR (0.48) TSHRFAAHCES2CES1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4222180-B1 BIS(HETEROCYCLIC-OLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-04-10 EP disclosed
US-20230357454-A1 Methods for Delivery of Non-Aromatic Solutions to Polymerization Reactors EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-11-09 US disclosed
US-11732063-B2 Lewis base catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-22 US disclosed
EP-4222180-A1 BIS(HETEROCYCLIC-OLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF ExxonMobil Chemical Patents Inc. (US) 2023-08-09 EP disclosed
CN-116323694-A Bis (heterocyclic-alkoxide) lewis base catalysts and methods thereof 埃克森美孚化学专利公司 2023-06-23 CN disclosed
EP-4192888-A1 METHODS FOR DELIVERY OF NON-AROMATIC SOLUTIONS TO POLYMERIZATION REACTORS ExxonMobil Chemical Patents Inc. (US) 2023-06-14 EP disclosed
CN-116209683-A Method for delivering non-aromatic solutions to a polymerization reactor 埃克森美孚化学专利公司 2023-06-02 CN disclosed
CN-113423744-B Lewis base catalyst and method thereof 埃克森美孚化学专利公司 2023-05-05 CN disclosed
CN-113423742-B Bis (arylphenoxide) lewis base catalysts and methods thereof 埃克森美孚化学专利公司 2023-05-05 CN disclosed
US-11572423-B2 Processes for introduction of liquid activators in olefin polymerization reactions EXXONMOBIL CHEMICALS PATENTS INC. (US) 2023-02-07 US disclosed
US-20210122844-A1 Catalyst Systems Including Phenol-Oxadiazole Catalyst and Non-Coordinating Anion Type Activators Containing Cation Having Alkyl Groups and uses Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2021-04-29 US disclosed
EP-3784648-A1 NON-COORDINATING ANION TYPE ACTIVATORS CONTAINING CATION HAVING BRANCHED ALKYL GROUPS ExxonMobil Chemical Patents Inc. (US) 2021-03-03 EP disclosed
CN-112020491-A Non-coordinating anionic activators containing cations with branched alkyl groups 埃克森美孚化学专利公司 2020-12-01 CN disclosed
WO-2020167838-A1 LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-08-20 WO disclosed
WO-2020167824-A1 B!S(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-08-20 WO disclosed
WO-2020167819-A1 LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-08-20 WO disclosed
US-20200255556-A1 Lewis Base Catalysts and Methods Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2020-08-13 US disclosed
US-20200254431-A1 BIS(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. 2020-08-13 US disclosed
US-20200255555-A1 Lewis Base Catalysts and Methods Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2020-08-13 US disclosed
US-20190330392-A1 Non-Coordinating Anion Type Activators Containing Cation having Branched Alkyl Groups EXXONMOBIL CHEMICALPATENTS INC. 2019-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11732063-B2 Lewis base catalysts and methods thereof TEC, ALOX12, ELL TSHR 3939/4885FAAH 755/4885CES2 1830/4885
US-20200255555-A1 Lewis Base Catalysts and Methods Thereof ELL, PHKB, POLI TSHR 3460/4885FAAH 1483/4885CES2 1297/4885
US-20190330392-A1 Non-Coordinating Anion Type Activators Containing Cation having Branched Alkyl Groups KCNK10, HCN4, KCNK4 TSHR 2117/4885FAAH 3114/4885CES2 2952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.