Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HAT1 | O14929 | 2/20 | 0.47 |
| ▸ | RBBP7 | Q16576 | 2/20 | 0.47 |
| ▸ | TST | Q16762 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21524596 | 0.80 | MEN1 (0.60) | KDM4EHPGDALDH1A1HTTMAPT | |
| SCHEMBL3834002 | 0.73 | KDM4E (0.61) | KDM4EHPGDALDH1A1HTTGAA | |
| SCHEMBL11375526 | 0.71 | TDP1 (0.60) | KDM4EHPGDALDH1A1HTTGAA | |
| SCHEMBL11384276 | 0.70 | TDP1 (0.55) | KDM4EHPGDALDH1A1HTTGAA | |
| SCHEMBL23965851 | 0.69 | MEN1 (0.72) | KDM4EHPGDALDH1A1HTTGAA | |
| SCHEMBL21524607 | 0.68 | MEN1 (0.45) | KDM4EHPGDALDH1A1HTTGAA | |
| SCHEMBL24193387 | 0.67 | TDP2 (0.46) | KDM4EHPGDALDH1A1HTTGAA | |
| SCHEMBL22830405 | 0.67 | MEN1 (0.68) | KDM4EHPGDALDH1A1HTTGAA | |
| SCHEMBL11389527 | 0.64 | MEN1 (0.52) | KDM4EHPGDALDH1A1HTTGAA | |
| SCHEMBL25166750 | 0.64 | MEN1 (0.80) | KDM4EHPGDALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10457682-B2 | Small molecules that bind MR1 | THE UNIVERSITY OF CHICAGO | 2019-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10457682-B2 | Small molecules that bind MR1 | MICA, HLA-DRB1, CD74 | KDM4E 4513/4885HPGD 3082/4885ALDH1A1 2498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.