Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.52 |
| ▸ | ITGAV | P06756 | 7/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.52 |
| ▸ | MC4R | P32245 | 9/20 | 0.50 |
| ▸ | MC5R | P33032 | 9/20 | 0.50 |
| ▸ | MC3R | P41968 | 9/20 | 0.50 |
| ▸ | MC1R | Q01726 | 9/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.50 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21524963 | 0.95 | ITGB3 (0.54) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL21524962 | 0.94 | ITGB3 (0.52) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL26220055 | 0.93 | ITGB3 (0.52) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL21766911 | 0.90 | ITGB3 (0.58) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL19605458 | 0.90 | ITGB3 (0.58) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL20888358 | 0.90 | ITGB3 (0.58) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL11948349 | 0.90 | MC4R (0.51) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL21524973 | 0.89 | ITGB3 (0.52) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL22970320 | 0.88 | ITGB3 (0.55) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL12148757 | 0.88 | ITGB3 (0.55) | ITGB3ITGAVITGB1ITGA5MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348529-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES | FORSCHUNGSVERBUND BERLIN EV (DE) | 2023-11-02 | — | — | US | disclosed |
| US-11746124-B2 | Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2023-09-05 | — | — | US | disclosed |
| US-20220106356-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES | FORSCHUNGSVERBUND BERLIN EV (DE) | 2022-04-07 | — | — | US | disclosed |
| US-11161873-B2 | Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2021-11-02 | — | — | US | disclosed |
| US-20190330264-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220106356-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES | PFAS, PHOSPHO1, PNKP | ITGB3 408/4885ITGAV 60/4885ITGB1 386/4885 |
| US-20190330264-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES | PHOSPHO1, PFAS, PNKP | ITGB3 452/4885ITGAV 107/4885ITGB1 479/4885 |
| US-11161873-B2 | Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates | TST, PHOSPHO1, TMT1A | ITGB3 843/4885ITGAV 333/4885ITGB1 832/4885 |
| US-20230348529-A1 | CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES | PFAS, PHOSPHO1, PNKP | ITGB3 408/4885ITGAV 60/4885ITGB1 386/4885 |
| US-11746124-B2 | Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates | PFAS, PHOSPHO1, PNKP | ITGB3 408/4885ITGAV 60/4885ITGB1 386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.