SCHEMBL21525

SCHEMBL21525

CC(C)(C)C1C[C]1c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
NISCH Q9Y2I1 1/20 0.31
KMT2A Q03164 1/20 0.30
MT-CO2 P00403 1/20 0.30
ALOX5 P09917 1/20 0.30
USP2 O75604 1/20 0.30
LMNA P02545 1/20 0.30
SLC22A2 O15244 1/20 0.30
SLC22A1 O15245 1/20 0.30
SLC22A3 O75751 1/20 0.30
SLC6A4 P31645 1/20 0.30
MAPK1 P28482 1/20 0.30
BRD4 O60885 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28431861 0.70 ALDH1A1 (0.42) ALDH1A1MAOAMAOBNISCHKMT2A
SCHEMBL9130854 0.70 ALDH1A1 (0.42) ALDH1A1MAOAMAOBNISCHKMT2A
SCHEMBL145371 0.67 MAOB (0.44) ALDH1A1MAOAMAOBLMNA
SCHEMBL14973844 0.65 ALDH1A1 (0.42) ALDH1A1MAOBLMNAMAPK1
SCHEMBL14974371 0.65 ALDH1A1 (0.42) ALDH1A1MAOBMAPK1
SCHEMBL695560 0.65 ALDH1A1 (0.42) ALDH1A1MAOBNISCHLMNAMAPK1
SCHEMBL17652437 0.65 ALDH1A1 (0.42) ALDH1A1MAOAMAOBLMNAMAPK1
Biphenyl SCHEMBL27745920 0.65 ALDH1A1 (0.69) ALDH1A1MAOALMNASLC22A2SLC22A1
SCHEMBL2537581 0.62 ALDH1A1 (0.38) ALDH1A1MAOAMAOBNISCH
SCHEMBL1224368 0.62 CFTR (0.48) ALDH1A1MAOAMAOBKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3253561-B1 PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER BOREALIS AG (AT) 2019-05-08 EP claimed
US-10105908-B2 Process for producing modified olefin polymer in an extruder BOREALIS AG (AT) 2018-10-23 US claimed
US-20170361543-A1 Process for Producing Modified Olefin Polymer in an Extruder BOREALIS AG (AT) 2017-12-21 US claimed
WO-2016124617-A1 PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER BOREALIS AG (AT) 2016-08-11 WO claimed
EP-4086299-B1 THERMALLY TREATED BIAXIALLY ORIENTED POLYPROPYLENE FILM BOREALIS AG (AT) 2024-07-03 EP disclosed
EP-4393969-A1 PROPYLENE COMPOSITION Borealis AG (AT) 2024-07-03 EP disclosed
EP-3898237-B1 BIAXIALLY ORIENTED POLYPROPYLENE FILM WITH IMPROVED SURFACE PROPERTIES BOREALIS AG (AT) 2024-04-17 EP disclosed
EP-3487927-B1 STIFF PROPYLENE COMPOSITION WITH GOOD DIMENSIONAL STABILITY AND EXCELLENT SURFACE APPEARANCE BOREALIS AG (AT) 2024-03-27 EP disclosed
EP-3532540-B1 HIGH FLOW HETEROPHASIC POLYPROPYLENE COPOLYMERS WITH IMPROVED MECHANICAL AND OPTICAL PROPERTIES BOREALIS AG (AT) 2024-03-13 EP disclosed
US-20230405969-A1 MULTILAYER SHEET COMPRISING A FOAMED LAYER SUITABLE FOR FOOD PACKAGING BOREALIS AG (AT) 2023-12-21 US disclosed
CN-117203269-A Biaxially oriented polypropylene film after heat treatment 博里利斯股份公司 2023-12-08 CN disclosed
US-20230227620-A1 HMS PP FOAM SHEET WITH GOOD COMPRESSIVE STRENGTH AND RECOVERABILITY BOREALIS AG (AT) 2023-07-20 US disclosed
US-20010016628-A1 Modified with less than 5% by weight of monofunctional, difunctional and polyfunctional monomers; improved melt processability; sheets, films, panels, coatings, pipes, hollow objects and foams BOREALIS GMBH (AU) 2001-08-23 US disclosed
US-6242525-B1 PROPYLENE HOMOPOLYMERS AND/OR COPOLYMERS WITH ELASTOMERS OF READILY VOLATILE DIENES IN THE PRESENCE OF THERMALLY DECOMPOSING FREE RADICAL-FORMING AGENTS; THERMOPLASTIC ELASTOMERS WITH A FINE DISPERSION DISTRIBUTION BOREALIS GMBH (AT) 2001-06-05 US disclosed
US-6225366-B1 USED IN PACKAGING SECTOR, MOTOR VEHICLE PARTS, SPORTS AND LEISURE EQUIPMENT, INDUSTRIAL APPLICATIONS, AS WELL AS APPLICATIONS IN THE BUILDING MATERIAL BOREALIS AG (AT) 2001-05-01 US disclosed
US-6218011-B1 Polyolefin fibers and polyolefin yarns and textile fabrics produced therefrom BOREALIS GMBH (AT) 2001-04-17 US disclosed
US-6204348-B1 REACTING A POLYPROPYLENE WITH ETHYLENICALLY UNSATURATED MONOMER BOREALIS GMBH (AT) 2001-03-20 US disclosed
US-6136926-A CURING WITH ETHYLENICALLY UNSATURATED ORGANOSILANE COMPOUND; HEATING BELOW SOFTENING POINT BOREALIS GMBH (AT) 2000-10-24 US disclosed
US-5962594-A Segmented polyolefins BOREALIS AG (AT) 1999-10-05 US disclosed
US-5929127-A Fine-celled polyolefin foam materials BOREALIS AG (AT) 1999-07-27 US disclosed