SCHEMBL215253

SCHEMBL215253

NCCNC[C@@H](N)CCCCNC(=O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 5/20 0.51
HDAC2 Q92769 5/20 0.51
HDAC3 O15379 4/20 0.51
HDAC8 Q9BY41 4/20 0.51
HDAC6 Q9UBN7 4/20 0.51
HDAC4 P56524 3/20 0.51
HDAC7 Q8WUI4 3/20 0.51
HDAC10 Q969S8 3/20 0.51
HDAC11 Q96DB2 3/20 0.51
HDAC9 Q9UKV0 3/20 0.51
HDAC5 Q9UQL6 3/20 0.51
NAAA Q02083 1/20 0.51
EPHX2 P34913 1/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
GRIN1 Q05586 3/20 0.48
GRIN2A Q12879 3/20 0.48
NCOR2 Q9Y618 1/20 0.48
GRIN2B Q13224 1/20 0.45
DRD2 P14416 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18435782 1.00 HDAC1 (0.51) HDAC1HDAC2HDAC3HDAC8HDAC6
SCHEMBL13257066 0.84 GRIN1 (0.39) GRIN1GRIN2AGRIN2B
SCHEMBL5855204 0.79 HDAC1 (0.67) HDAC1HDAC2HDAC3HDAC8HDAC6
SCHEMBL24130547 0.79 HDAC1 (0.58) HDAC1HDAC2HDAC3HDAC8HDAC6
SCHEMBL345305 0.79 HDAC1 (0.58) HDAC1HDAC2HDAC3HDAC8HDAC6
SCHEMBL1242961 0.79 HDAC1 (0.58) HDAC1HDAC2HDAC3HDAC8HDAC6
SCHEMBL215653 0.78 RAB9A (0.41) HDAC1HDAC2HDAC3HDAC8HDAC6
SCHEMBL15065079 0.78 GRIN1 (0.63) HDAC1HDAC2HDAC3HDAC8HDAC6
SCHEMBL3869201 0.78 HDAC1 (0.70) HDAC1HDAC2HDAC3HDAC8HDAC6
SCHEMBL4426060 0.78 HDAC1 (0.70) HDAC1HDAC2HDAC3HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4134667-A1 APPARATUS FOR MEASURING ANALYTES USING FET ARRAYS Life Technologies Corporation (US) 2023-02-15 EP disclosed
US-9269708-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2016-02-23 US disclosed
US-8530941-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2013-09-10 US disclosed
US-8426898-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2013-04-23 US disclosed
US-8426899-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2013-04-23 US disclosed
US-20120322054-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-12-20 US disclosed
US-8269261-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-09-18 US disclosed
US-8264014-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-09-11 US disclosed
US-20120135870-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-05-31 US disclosed
US-20120129728-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-05-24 US disclosed
US-20120055811-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-03-08 US disclosed
US-20120055813-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-03-08 US disclosed
US-20120045844-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (US) 2012-02-23 US disclosed
US-20120040844-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-02-16 US disclosed
US-20120037961-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-02-16 US disclosed
US-20120034607-A1 Methods and apparatus for measuring analytes using large scale fet arrays Life Technologies Corporation (US) 2012-02-09 US disclosed
US-7948015-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2011-05-24 US disclosed
US-20100197507-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS ION TORRENT SYSTEMS INCORPORATED (US) 2010-08-05 US disclosed
US-20100188073-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS ION TORRENT SYSTEMS INCORPORATED (US) 2010-07-29 US disclosed
US-20090127589-A1 Methods and apparatus for measuring analytes using large scale FET arrays ION TORRENT SYSTEMS INCORPORATED (US) 2009-05-21 US disclosed