SCHEMBL215653

SCHEMBL215653

C=Cc1ccc(/C=N/CCNCC/N=C/c2ccc(/C=N/CCNCC(N)CCCCNC(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.41
MAPT P10636 2/20 0.41
KDM4E B2RXH2 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPC1 O15118 2/20 0.40
HDAC1 Q13547 4/20 0.39
HDAC2 Q92769 4/20 0.39
HDAC8 Q9BY41 4/20 0.39
HDAC6 Q9UBN7 4/20 0.39
GRIN1 Q05586 2/20 0.39
GRIN2A Q12879 2/20 0.39
HDAC3 O15379 3/20 0.39
HDAC4 P56524 3/20 0.39
HDAC7 Q8WUI4 3/20 0.39
HDAC10 Q969S8 3/20 0.39
HDAC11 Q96DB2 3/20 0.39
HDAC9 Q9UKV0 3/20 0.39
HDAC5 Q9UQL6 3/20 0.39
NAAA Q02083 1/20 0.39
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10050880 0.89 GRIN1 (0.32) GRIN1GRIN2A
SCHEMBL215253 0.78 HDAC1 (0.51) RAB9ANPC1HDAC1HDAC2HDAC8
SCHEMBL18435782 0.78 HDAC1 (0.51) RAB9ANPC1HDAC1HDAC2HDAC8
SCHEMBL26417166 0.70 MAPK1 (0.56) RAB9ANPC1HDAC1HDAC2HDAC8
SCHEMBL8744962 0.69 MAPK1 (0.59) RAB9ANPC1HDAC1HDAC2HDAC8
SCHEMBL216180 0.68 ALDH1A1 (0.38) KDM4E
SCHEMBL28472074 0.67 NAAA (0.59) RAB9ASMN1; SMN2NPC1HDAC1HDAC2
SCHEMBL24130547 0.67 HDAC1 (0.58) RAB9AKDM4ESMN1; SMN2NPC1HDAC1
SCHEMBL1242961 0.67 HDAC1 (0.58) RAB9AKDM4ESMN1; SMN2NPC1HDAC1
SCHEMBL345305 0.67 HDAC1 (0.58) RAB9AKDM4ESMN1; SMN2NPC1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120322054-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-12-20 US disclosed
US-8306757-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-11-06 US disclosed
US-8269261-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-09-18 US disclosed
US-8264014-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-09-11 US disclosed
US-20120135870-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-05-31 US disclosed
US-20120129732-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-05-24 US disclosed
US-20120129703-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-05-24 US disclosed
US-20120129728-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-05-24 US disclosed
US-20120055811-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-03-08 US disclosed
US-20120055813-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-03-08 US disclosed
US-20120045844-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (US) 2012-02-23 US disclosed
US-20120040844-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-02-16 US disclosed
US-20120037961-A1 Methods and Apparatus for Measuring Analytes Using Large Scale FET Arrays Life Technologies Corporation (US) 2012-02-16 US disclosed
US-20120034607-A1 Methods and apparatus for measuring analytes using large scale fet arrays Life Technologies Corporation (US) 2012-02-09 US disclosed
US-7948015-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2011-05-24 US disclosed
US-20100197507-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS ION TORRENT SYSTEMS INCORPORATED (US) 2010-08-05 US disclosed
US-20100188073-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS ION TORRENT SYSTEMS INCORPORATED (US) 2010-07-29 US disclosed
US-20090127589-A1 Methods and apparatus for measuring analytes using large scale FET arrays ION TORRENT SYSTEMS INCORPORATED (US) 2009-05-21 US disclosed