SCHEMBL215268

SCHEMBL215268

Cc1ccc2c(c1)C=C[CH]2

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.38
CYP2A6 P11509 3/20 0.38
TDP1 Q9NUW8 5/20 0.33
ACHE P22303 3/20 0.33
TP53 P04637 2/20 0.33
ALOX15 P16050 2/20 0.33
CYP3A4 P08684 1/20 0.33
THRB P10828 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TRPA1 O75762 1/20 0.33
ALDH1A1 P00352 2/20 0.32
NCK1 P16333 1/20 0.30
BACE1 P56817 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28330225 0.98 CYP1A2 (0.36) CYP1A2CYP2A6TDP1ACHETP53
SCHEMBL28041918 0.91 CYP1A2 (0.32) CYP1A2CYP2A6
SCHEMBL218215 0.90 CYP1A2 (0.38) CYP1A2CYP2A6TDP1ACHETP53
SCHEMBL7793893 0.78
SCHEMBL3847079 0.70
SCHEMBL7794547 0.70 CA12 (0.34) CYP2A6TDP1ALOX15ALDH1A1BACE1
SCHEMBL27314310 0.70 ALDH1A1 (0.42) CYP2A6TDP1TP53ALOX15CYP3A4
SCHEMBL714777 0.70 ALDH1A1 (0.40) CYP1A2TDP1ALOX15SMN1; SMN2ALDH1A1
SCHEMBL26882 0.70 TRPA1 (0.40) CYP1A2CYP2A6TP53SMN1; SMN2TRPA1
SCHEMBL28152728 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5627244-A SOLVENT RESISTANT POLYMETHACRYLATE SUMITOMO CHEMICAL CO., LTD. (JP) 1997-05-06 US claimed
US-6414090-B1 None US disclosed
EP-3694811-B1 SUPPORTED CATALYST SYSTEM BASELL POLYOLEFINE GMBH (DE) 2024-04-03 EP disclosed
EP-3587457-B1 METHOD OF TRANSFERRING SLURRY AND METHOD OF PRODUCING POLYOLEFIN SUMITOMO CHEMICAL CO (JP) 2023-09-27 EP disclosed
US-11518824-B2 Supported catalyst system BASELL POLYOLEFINE GMBH (DE) 2022-12-06 US disclosed
CN-113402641-B Metallocene catalyst, preparation method and application 北京化工大学 2022-09-20 CN disclosed
US-11352448-B2 Method of transferring slurry, method of producing polyolefin, and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-06-07 US disclosed
CN-110639434-B Method for transferring slurry, method for producing polyolefin, and use thereof 住友化学株式会社 2022-05-17 CN disclosed
CN-110483670-B Metallocene complex and process for producing olefin polymer 日本聚丙烯株式会社 2021-11-30 CN disclosed
CN-113402641-A Metallocene catalyst, preparation method and application 北京化工大学 2021-09-17 CN disclosed
EP-1113025-A2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-04 EP disclosed
US-6214954-B1 HOMO OR COPOLYMERIZING AN OLEFIN WITH POLYMERIZATION CATALYST COMPRISING A TRANSITION METAL COMPOUND, CYCLOPENTADIENYL RING CONTAINING LIGAND AND A CHELATING LIGAND, PRODUCES POLYMER WITH NARROW MOLECULAR WEIGHT DISTRIBUTION AND UNIFORMITY ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-04-10 US disclosed
EP-0798313-B1 OLEFIN POLYMERIZATION CATALYST ASAHI CHEMICAL IND (JP) 2001-03-21 EP disclosed
EP-0985673-A2 Modified aluminium oxy compound, polymerization catalyst and process for producing olefin polymer and alkenyl aromatic hydrocarbon polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-03-15 EP disclosed
CN-1049899-C Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM NV (NL) 2000-03-01 CN disclosed
EP-0970964-A2 Method for producing titanium complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-01-12 EP disclosed
CN-1169736-A Catalyst for olefin polymerization ASAHI CHEMICAL IND (JP) 1998-01-07 CN disclosed
EP-0798313-A1 OLEFIN POLYMERIZATION CATALYST Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1997-10-01 EP disclosed
US-5627244-A SOLVENT RESISTANT POLYMETHACRYLATE SUMITOMO CHEMICAL CO., LTD. (JP) 1997-05-06 US disclosed
CN-1128272-A Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM NV (NL) 1996-08-07 CN disclosed