SCHEMBL218215

SCHEMBL218215

Cc1ccc2c(c1)[CH]C=C2

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.38
CYP2A6 P11509 3/20 0.38
TDP1 Q9NUW8 5/20 0.33
ACHE P22303 3/20 0.33
CYP3A4 P08684 2/20 0.33
TP53 P04637 2/20 0.33
ALOX15 P16050 2/20 0.33
THRB P10828 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TRPA1 O75762 1/20 0.33
TSHR P16473 1/20 0.32
ALDH1A1 P00352 3/20 0.32
MAPK1 P28482 1/20 0.32
NCK1 P16333 1/20 0.30
BACE1 P56817 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL215268 0.90 CYP1A2 (0.38) CYP1A2CYP2A6TDP1ACHECYP3A4
SCHEMBL28330225 0.88 CYP1A2 (0.36) CYP1A2CYP2A6TDP1ACHECYP3A4
SCHEMBL28041918 0.82 CYP1A2 (0.32) CYP1A2CYP2A6
SCHEMBL7793893 0.78
SCHEMBL7793703 0.75 TP53 (0.36) CYP2A6TDP1CYP3A4TP53ALOX15
SCHEMBL3847079 0.70
SCHEMBL7784962 0.70 CA12 (0.34) CYP2A6TDP1ALOX15ALDH1A1MAPK1
SCHEMBL27338971 0.70 CA12 (0.39) ACHE
SCHEMBL28152728 0.69
SCHEMBL244456 0.67 CNR1 (0.42) CYP3A4TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3587457-B1 METHOD OF TRANSFERRING SLURRY AND METHOD OF PRODUCING POLYOLEFIN SUMITOMO CHEMICAL CO (JP) 2023-09-27 EP disclosed
US-11352448-B2 Method of transferring slurry, method of producing polyolefin, and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-06-07 US disclosed
CN-110639434-B Method for transferring slurry, method for producing polyolefin, and use thereof 住友化学株式会社 2022-05-17 CN disclosed
EP-3130635-B1 RESIN COMPOSITION, CROSS-LINKED PRODUCT, AND METHOD FOR MANUFACTURING CROSS-LINKED PRODUCT SUMITOMO CHEMICAL CO (JP) 2020-02-26 EP disclosed
CN-110639434-A Method for transferring slurry, method for producing polyolefin, and use thereof 住友化学株式会社 2020-01-03 CN disclosed
CN-106459523-B The manufacturing method of resin combination, cross-linking agent and cross-linking agent 住友化学株式会社 2019-11-19 CN disclosed
US-10421921-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-24 US disclosed
US-9909002-B2 Resin composition, cross-linked product, and method for manufacturing cross-linked product SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-03-06 US disclosed
EP-1920031-B1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-01-10 EP disclosed
CN-104327200-B The preparation method of polyalphaolefin 埃克森美孚化学专利公司 2017-07-14 CN disclosed
US-20010041775-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-11-15 US disclosed
US-20010020075-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-06 US disclosed
EP-1113025-A2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-04 EP disclosed
EP-1113026-A2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-04 EP disclosed
EP-0575123-B1 Ethylene copolymer composition MITSUI CHEMICALS INC (JP) 2000-08-30 EP disclosed
EP-0985673-A2 Modified aluminium oxy compound, polymerization catalyst and process for producing olefin polymer and alkenyl aromatic hydrocarbon polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-03-15 EP disclosed
CN-1049899-C Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM NV (NL) 2000-03-01 CN disclosed
CN-1128272-A Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM NV (NL) 1996-08-07 CN disclosed
US-5371146-A A blends of ethylene-(alpha)olefins copolymers has high transparency, high strength, blocking resistance, good melt flowability and tension MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-12-06 US disclosed
EP-0575123-A2 Ethylene copolymer composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-12-22 EP disclosed