Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12462929 | 0.91 | MET (0.72) | METMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2152552 | 0.90 | MET (0.57) | METMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2153009 | 0.88 | MET (0.71) | MET | |
| SCHEMBL12463183 | 0.87 | MET (0.71) | METMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL12462941 | 0.87 | MET (0.71) | METMAPTSMN1; SMN2 | |
| SCHEMBL12462938 | 0.84 | MET (0.74) | METMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2152501 | 0.84 | MET (0.65) | METHRH3 | |
| SCHEMBL12462921 | 0.83 | MET (0.71) | METHDAC1 | |
| SCHEMBL3117528 | 0.83 | MET (0.59) | METMAPTMEN1KMT2A | |
| SCHEMBL2672593 | 0.82 | ALDH1A1 (0.59) | METMAPTMEN1KMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152370-B1 | ARYL ETHER PYRIDAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2011-07-06 | — | — | EP | claimed |