Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 9/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12462920 | 0.90 | MET (0.72) | METMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2152910 | 0.90 | MET (0.61) | METHRH3MAPTSMN1; SMN2MEN1 | |
| SCHEMBL2153009 | 0.89 | MET (0.71) | MET | |
| SCHEMBL12463577 | 0.88 | MET (0.71) | MET | |
| SCHEMBL12462938 | 0.86 | MET (0.74) | METMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2152501 | 0.84 | MET (0.65) | METHRH3 | |
| SCHEMBL3117528 | 0.84 | MET (0.59) | METMAPTMEN1KMT2A | |
| SCHEMBL2672593 | 0.83 | ALDH1A1 (0.59) | METMAPTMEN1KMT2A | |
| SCHEMBL2469567 | 0.83 | MET (0.67) | METMEN1KMT2A | |
| SCHEMBL2472096 | 0.82 | MET (0.56) | METMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152370-B1 | ARYL ETHER PYRIDAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2011-07-06 | — | — | EP | claimed |