Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PPIB | P23284 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20399024 | 1.00 | KDM1A (0.52) | KDM1AMAOASMN1; SMN2LMNACACNA1B | |
| SCHEMBL1131712 | 0.84 | DPP4 (0.40) | KDM1AMAOASMN1; SMN2LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL27149878 | 0.82 | GNAI3 (0.44) | KDM1AMAOACACNA1BGNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL27149879 | 0.82 | GNAI3 (0.44) | KDM1AMAOACACNA1BGNAI3GNAO1 | |
| SCHEMBL12765271 | 0.81 | KDM1A (0.50) | KDM1AMAOASMN1; SMN2LMNACACNA1B | |
| SCHEMBL12765231 | 0.81 | KDM1A (0.50) | KDM1AMAOASMN1; SMN2LMNACACNA1B | |
| SCHEMBL25266002 | 0.81 | DPP4 (0.40) | KDM1AMAOASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL25202270 | 0.81 | DPP4 (0.40) | KDM1AMAOASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL16060949 | 0.78 | SMN1; SMN2 (0.35) | KDM1AMAOASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL16060951 | 0.78 | SMN1; SMN2 (0.35) | KDM1AMAOASMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210379044-A1 | NON PEPTIDIC HETEROBIVALENT MOLECULES FOR TREATING INFLAMMATORY DISEASES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED | 2021-12-09 | — | — | US | disclosed |
| US-20190336489-A1 | NON PEPTIDE HETEROBIVALENT MOLECULES FOR TREATING INFLAMMATORY DISEASES | GLAXOSMITHKLINE IP DEV LTD (GB) | 2019-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210379044-A1 | NON PEPTIDIC HETEROBIVALENT MOLECULES FOR TREATING INFLAMMATORY DISEASES | ACKR3, CXCR3, CCL2 | KDM1A 4648/4885MAOA 4813/4885SMN1; SMN2 4407/4885 |
| US-20190336489-A1 | NON PEPTIDE HETEROBIVALENT MOLECULES FOR TREATING INFLAMMATORY DISEASES | ACKR3, CXCR3, CCL2 | KDM1A 4713/4885MAOA 4818/4885SMN1; SMN2 4272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.