Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.75 |
| ▸ | NPC1 | O15118 | 8/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.75 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.73 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.70 |
| ▸ | POLB | P06746 | 3/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27790138 | 0.89 | NPC1 (0.80) | RAB9ANPC1KMT2AHSP90AA1ALOX12 | |
| SCHEMBL27790128 | 0.88 | NPC1 (0.86) | RAB9ANPC1KMT2AHSP90AA1ALOX12 | |
| SCHEMBL20530711 | 0.88 | RAB9A (0.79) | RAB9ANPC1KMT2AHSP90AA1ALOX12 | |
| SCHEMBL2153168 | 0.86 | RAB9A (1.00) | RAB9ANPC1KMT2AHSP90AA1ALOX12 | |
| SCHEMBL1811300 | 0.84 | NPC1 (1.00) | RAB9ANPC1KMT2AHSP90AA1ALOX12 | |
| SCHEMBL4039804 | 0.84 | NPC1 (0.75) | RAB9ANPC1KMT2AHSP90AA1ALOX12 | |
| SCHEMBL4035597 | 0.83 | NPC1 (0.86) | RAB9ANPC1KMT2AHSP90AA1ALOX12 | |
| SCHEMBL4045007 | 0.83 | NPC1 (0.78) | RAB9ANPC1KMT2AHSP90AA1ALOX12 | |
| SCHEMBL4037950 | 0.83 | NPC1 (0.85) | RAB9ANPC1KMT2AHSP90AA1ALOX12 | |
| SCHEMBL2153766 | 0.83 | NPC1 (0.86) | RAB9ANPC1KMT2AHSP90AA1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295890-A1 | GLYCOSAMINOGLYCAN INHIBITORS | Zacharon Pharmaceutical, Inc. (US) | 2012-11-22 | — | — | US | disclosed |
| WO-2011082175-A2 | GLYCOSAMINOGLYCAN INHIBITORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295890-A1 | GLYCOSAMINOGLYCAN INHIBITORS | CSGALNACT1, FUT5, ST3GAL3 | RAB9A 4336/4885NPC1 1684/4885KMT2A 4294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.