Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | IL1B | P01584 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6047196 | 0.82 | CYP2C9 (0.43) | P2RX7CYP2C9NAMPTGABRA5 | |
| SCHEMBL21617369 | 0.80 | P2RX7 (0.58) | P2RX7ALDH1A1MAPTCYP2C9NAMPT | |
| SCHEMBL17886855 | 0.78 | CYP2C9 (0.42) | P2RX7ALDH1A1GAACYP2C9NAMPT | |
| SCHEMBL17888348 | 0.78 | GAA (0.42) | P2RX7GAACYP2C9NAMPTGABRA5 | |
| Hydrochloric Acid SCHEMBL31169752 | 0.78 | CYP2C9 (0.42) | P2RX7ALDH1A1CYP2C9NAMPT | |
| SCHEMBL8550272 | 0.77 | ADRA2C (0.46) | P2RX7CYP2C9NAMPTGABRA5ADORA2A | |
| SCHEMBL261850 | 0.77 | — | — | |
| SCHEMBL13401252 | 0.76 | KDM1A (0.43) | P2RX7ALDH1A1GAAMAPTIDO1 | |
| SCHEMBL13731868 | 0.76 | CYP2C9 (0.59) | P2RX7ALDH1A1GAAMAPTCYP2C9 | |
| Hydrochloric Acid SCHEMBL5010799 | 0.75 | DPP4 (0.44) | P2RX7CYP2C9NAMPTNOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190330181-A1 | HEMOGLOBIN MODIFIER COMPOUNDS AND USES THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330181-A1 | HEMOGLOBIN MODIFIER COMPOUNDS AND USES THEREOF | HBB, HBG1, HBG2 | P2RX7 4755/4885ALDH1A1 863/4885GAA 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.