Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23997616 | 0.84 | GNAO1 (0.44) | SMN1; SMN2HRH3EPHX1EPHX2 | |
| SCHEMBL31273888 | 0.79 | HRH3 (0.49) | SMN1; SMN2HRH3EPHX1EPHX2HSD11B1 | |
| SCHEMBL178287 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2HRH3EPHX1EPHX2HSD11B1 | |
| SCHEMBL22793920 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2HRH3EPHX1EPHX2HSD11B1 | |
| SCHEMBL17574097 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2HRH3EPHX1EPHX2HSD11B1 | |
| SCHEMBL3532163 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2HRH3EPHX1EPHX2HSD11B1 | |
| SCHEMBL22520700 | 0.75 | ACHE (0.50) | SMN1; SMN2HRH3HSD11B1KDM4EACHE | |
| SCHEMBL102378 | 0.75 | NCF1 (0.58) | SMN1; SMN2HRH3EPHX1EPHX2HSD11B1 | |
| SCHEMBL2439300 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2HRH3EPHX1EPHX2HSD11B1 | |
| SCHEMBL772530 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2HRH3EPHX1EPHX2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3316877-B1 | ADO-RESISTANT CYSTEAMINE ANALOGS AND USES THEREOF | HORIZON ORPHAN LLC (US) | 2019-10-30 | — | — | EP | disclosed |