Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.39 |
| ▸ | CHRNG | P07510 | 4/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.39 |
| ▸ | CHRND | Q07001 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601332 | 1.00 | SLC6A3 (0.42) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL18653492 | 1.00 | SLC6A3 (0.42) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL21309260 | 0.91 | SLC6A3 (0.38) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL13575192 | 0.84 | SLC6A3 (0.39) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL27103249 | 0.84 | SLC6A3 (0.39) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL14296180 | 0.83 | SLC6A3 (0.38) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL25874319 | 0.80 | SLC6A3 (0.40) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL22349635 | 0.80 | — | — | |
| SCHEMBL18541495 | 0.80 | — | — | |
| SCHEMBL19524701 | 0.77 | EPHX1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306572-A1 | POLYMER HAVING HALOGEN-CONTAINING SEGMENT AND PHARMACEUTICAL COMPOSITION USING SAME | AGC INC. (JP) | 2024-01-17 | — | — | EP | disclosed |
| US-11793893-B2 | Compounds comprising conductive oligomers, materials formed therefrom, and methods of making and using same | THE PENN STATE RESEARCH FOUNDATION (PA) | 2023-10-24 | — | — | US | disclosed |
| US-20230279053-A1 | GLP-1 RECEPTOR ANTAGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2023-09-07 | — | — | US | disclosed |
| US-11407741-B2 | Compounds and their use as selective inhibitors of caspase-2 | Universite De Paris (FR) | 2022-08-09 | — | — | US | disclosed |
| US-20210316004-A1 | ANTIBODY MOLECULE-DRUG CONJUGATES AND USES THEREOF | Visterra, Inc. | 2021-10-14 | — | — | US | disclosed |
| US-10919938-B2 | Modified cyclopentapeptides and uses thereof | Technische Universität München (DE) | 2021-02-16 | — | — | US | disclosed |
| US-10744180-B2 | Therapy and kit for the prevention and treatment of cystic fibrosis | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2020-08-18 | — | — | US | disclosed |
| US-10626144-B2 | Peptide derivatives and uses thereof | NOSOPHARM (FR) | 2020-04-21 | — | — | US | disclosed |
| WO-2019163942-A1 | POLYMER, METHOD FOR PRODUCING POLYMER, DRUG COMPLEX, AND MICELLE | 公益財団法人川崎市産業振興財団 | 2019-08-29 | — | — | WO | disclosed |
| WO-2019163958-A1 | DRUG COMPOSITE, MICELLE, AND PHARMACEUTICAL COMPOSITION | 公益財団法人川崎市産業振興財団 | 2019-08-29 | — | — | WO | disclosed |
| EP-2393819-B1 | SILYL AND HETEROATOM SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZO PHOSPHOLES AND THE APPLICATION THEREOF IN ORGANIC ELECTRONICS | BASF SE (DE) | 2017-01-25 | — | — | EP | disclosed |
| US-20160257709-A1 | HEMIASTERLIN DERIVATIVES FOR CONJUGATION AND THERAPY | SUTRO BIOPHARMA, INC. | 2016-09-08 | — | — | US | disclosed |
| US-9266924-B2 | Cyclopentapeptide derivatives and uses thereof | Technische Universität München (DE) | 2016-02-23 | — | — | US | disclosed |
| US-20130129622-A1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | Technische Universität München (DE) | 2013-05-23 | — | — | US | disclosed |
| US-20080287347-A1 | Novel Lipopeptides as Antibacterial Agents | CUBIST PHARMACEUTICALS, INC. | 2008-11-20 | — | — | US | disclosed |
| US-7408025-B2 | Lipopeptides as antibacterial agents | CUBIST PHARMACEUTICALS, INC. (US) | 2008-08-05 | — | — | US | disclosed |
| US-7408025-B2 | Lipopeptides as antibacterial agents | CUBIST PHARMACEUTICALS, INC. (US) | 2008-08-05 | — | — | US | disclosed |
| US-20070244055-A1 | Conjugates useful in the treatment of prostate cancer | BRADY STEPHEN F | 2007-10-18 | — | — | US | disclosed |
| US-20070129309-A1 | Conjugates useful in the treatment of prostate cancer | BRADY STEPHEN F | 2007-06-07 | — | — | US | disclosed |
| US-20070021350-A1 | Conjugates useful in the treatment of prostate cancer | BRADY STEPHEN F | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279053-A1 | GLP-1 RECEPTOR ANTAGONISTS | GLP1R, GIPR, GCGR | SLC6A3 2927/4885SLC6A2 2802/4885CHRNA1 669/4885 |
| US-10626144-B2 | Peptide derivatives and uses thereof | VIP, IAPP, NGLY1 | SLC6A3 3598/4885SLC6A2 3729/4885CHRNA1 4785/4885 |
| US-20210316004-A1 | ANTIBODY MOLECULE-DRUG CONJUGATES AND USES THEREOF | CD14, EPCAM, CD44 | SLC6A3 1908/4885SLC6A2 2618/4885CHRNA1 2819/4885 |
| US-20160257709-A1 | HEMIASTERLIN DERIVATIVES FOR CONJUGATION AND THERAPY | CYP17A1, HSD17B7, SHBG | SLC6A3 3387/4885SLC6A2 2496/4885CHRNA1 2933/4885 |
| US-20080287347-A1 | Novel Lipopeptides as Antibacterial Agents | CLPTM1, NGLY1, VIP | SLC6A3 4826/4885SLC6A2 4850/4885CHRNA1 4877/4885 |
| US-20130129622-A1 | CYCLOPENTAPEPTIDE DERIVATIVES AND USES THEREOF | ANXA4, XPNPEP1, ANXA1 | SLC6A3 1254/4885SLC6A2 1576/4885CHRNA1 1673/4885 |
| US-20070129309-A1 | Conjugates useful in the treatment of prostate cancer | BPHL, KLK3, DNPEP | SLC6A3 2244/4885SLC6A2 2014/4885CHRNA1 3505/4885 |
| US-10744180-B2 | Therapy and kit for the prevention and treatment of cystic fibrosis | CFTR, CLCN2, PROKR1 | SLC6A3 4299/4885SLC6A2 4718/4885CHRNA1 1305/4885 |
| US-11793893-B2 | Compounds comprising conductive oligomers, materials formed therefrom, and methods of making and using same | PICALM, ILK, GJB2 | SLC6A3 2403/4885SLC6A2 1993/4885CHRNA1 3094/4885 |
| US-20070244055-A1 | Conjugates useful in the treatment of prostate cancer | BPHL, KLK3, DNPEP | SLC6A3 1810/4885SLC6A2 1714/4885CHRNA1 3551/4885 |
| US-10919938-B2 | Modified cyclopentapeptides and uses thereof | ANXA4, CPA4, PTMS | SLC6A3 382/4885SLC6A2 446/4885CHRNA1 1658/4885 |
| US-20070021350-A1 | Conjugates useful in the treatment of prostate cancer | BPHL, KLK3, DNPEP | SLC6A3 1810/4885SLC6A2 1714/4885CHRNA1 3551/4885 |
| US-11407741-B2 | Compounds and their use as selective inhibitors of caspase-2 | CASP2, CASP1, CASP3 | SLC6A3 4691/4885SLC6A2 4524/4885CHRNA1 4885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.