Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | CCR8 | P51685 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22004157 | 0.83 | ACLY (0.49) | KMT2AADRA2AKDM4EMAPTMEN1 | |
| SCHEMBL23320494 | 0.83 | CA12 (0.45) | KMT2AADRA2AKDM4EMAPTALDH1A1 | |
| SCHEMBL30943245 | 0.83 | CA12 (0.45) | KMT2AADRA2AKDM4EMAPTALDH1A1 | |
| SCHEMBL22004356 | 0.80 | KMT2A (0.53) | KMT2AADRA2AKDM4EMAPTMEN1 | |
| SCHEMBL10103705 | 0.79 | KMT2A (0.76) | KMT2AADRA2AKDM4EMAPTMEN1 | |
| SCHEMBL12278076 | 0.79 | CA12 (0.39) | KMT2AADRA2AKDM4EALDH1A1HPGD | |
| SCHEMBL12278039 | 0.79 | CA12 (0.39) | KMT2AADRA2AKDM4EMAPTALDH1A1 | |
| SCHEMBL12278294 | 0.78 | CA12 (0.43) | KDM4EMAPTALDH1A1HPGDCA12 | |
| SCHEMBL29533984 | 0.78 | KMT2A (0.50) | KMT2AADRA2AKDM4EMAPTMEN1 | |
| SCHEMBL11572827 | 0.78 | DAO (0.51) | KMT2AKDM4EMAPTHPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200157076-A1 | ACLY INHIBITORS AND USES THEREOF | NIMBUS DISCOVERY, INC. | 2020-05-21 | — | — | US | disclosed |
| US-20190334099-A1 | TRANSITION METAL COMPLEX AND APPLICATION THEREOF, MIXTURE AND ORGANIC ELECTRONIC DEVICE | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157076-A1 | ACLY INHIBITORS AND USES THEREOF | ACLY, ATP5ME, ATP5MG | KMT2A 1976/4885ADRA2A 4635/4885KDM4E 1181/4885 |
| US-20190334099-A1 | TRANSITION METAL COMPLEX AND APPLICATION THEREOF, MIXTURE AND ORGANIC ELECTRONIC DEVICE | AP1M1, MT-CO1, OSTC | KMT2A 2675/4885ADRA2A 4562/4885KDM4E 3936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.