Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | JAK3 | P52333 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1106481 | 0.83 | FGFR1 (0.49) | FGFR1JAK2JAK3HPGDHSD17B10 | |
| SCHEMBL1701476 | 0.73 | FGFR1 (0.49) | FGFR1JAK2JAK3HPGDHSD17B10 | |
| SCHEMBL29593970 | 0.70 | FGFR1 (0.53) | FGFR1JAK2JAK3HPGDHSD17B10 | |
| SCHEMBL256337 | 0.70 | FGFR1 (0.53) | FGFR1JAK2JAK3HPGDHSD17B10 | |
| SCHEMBL1106468 | 0.69 | NFATC1 (0.45) | FGFR1JAK2JAK3HPGDHSD17B10 | |
| SCHEMBL12763767 | 0.69 | POLB (0.53) | FGFR1JAK2JAK3USP2HTT | |
| SCHEMBL1743206 | 0.67 | ADA (0.63) | HSD17B10ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL20083791 | 0.67 | CYP3A4 (0.40) | GSK3BALDH1A1SMN1; SMN2 | |
| SCHEMBL14021996 | 0.67 | LTA4H (0.49) | FGFR1JAK2JAK3HPGDHSD17B10 | |
| SCHEMBL25291568 | 0.66 | FGFR1 (0.53) | FGFR1JAK2JAK3HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10464960-B2 | Salen complexes with dianionic counterions | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2019-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10464960-B2 | Salen complexes with dianionic counterions | NCLN, POLN, NCL | FGFR1 4530/4885JAK2 3383/4885JAK3 4026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.